Cent European J Urol. 2014;67(4):397-404. doi: 10.5173/ceju.2014.04.art16. Epub 2014 Dec 05.
Features of diagnostics and treatment of partial androgen deficiency of aging men.
Central European journal of urology
Alexander Pechersky
Affiliations
Affiliations
- Department of Urology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia.
PMID: 25667762
PMCID: PMC4310881 DOI: 10.5173/ceju.2014.04.art16
Abstract
INTRODUCTION: Decreasing of testosterone level is an important part of a male elderly.
MATERIAL AND METHODS: To describe this phenomenon a PubMed and national databases were searched for 17β-dehydrotestosterone, common testosterone, free testosterone, 17β-estradiol, luteinizing hormone, partial androgen deficiency of aging men.
RESULTS: The reduction in intensity of the processes of tissue renewal of the testicles results in a partial androgen deficiency of aging men. A decrease in the levels of total and free testosterone and an increase in the levels of 5α-dihydrotestosterone, 17β-estradiol, sex hormone binding globulin, LH and FSH, along with a decrease in the amplitude of the rhythm of incretion of LH, FSH and total testosterone will testify to a deficiency of testosterone.
CONCLUSIONS: It is very important to make an individualized selection of the dose of testosterone preparation which enters the blood plasma.
Keywords: 17β–estradiol; 5α–dehydrotestosterone; common testosterone; free testosterone; luteinizing hormone; partial androgen deficiency of aging men
References
- Int J Androl. 2002 Apr;25(2):119-25 - PubMed
- Tsitologiia. 2005;47(2):130-5 - PubMed
- J Androl. 1994 May-Jun;15(3):212-5 - PubMed
- Prostate. 1994;24(3):162-6 - PubMed
- Cent European J Urol. 2014;66(4):423-7 - PubMed
- J Clin Endocrinol Metab. 1991 Nov;73(5):1016-25 - PubMed
- Tsitologiia. 2008;50(6):511-20 - PubMed
- Endocrinology. 1993 Oct;133(4):1490-503 - PubMed
- Harvey Lect. 1969;63:47-71 - PubMed
- Neurosci Biobehav Rev. 1992 Fall;16(3):371-8 - PubMed
- Tsitologiia. 2006;48(10):862-6 - PubMed
- Tsitologiia. 2005;47(4):311-7 - PubMed
Publication Types