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Cent European J Urol. 2014;67(4):397-404. doi: 10.5173/ceju.2014.04.art16. Epub 2014 Dec 05.

Features of diagnostics and treatment of partial androgen deficiency of aging men.

Central European journal of urology

Alexander Pechersky

Affiliations

  1. Department of Urology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia.

PMID: 25667762 PMCID: PMC4310881 DOI: 10.5173/ceju.2014.04.art16

Abstract

INTRODUCTION: Decreasing of testosterone level is an important part of a male elderly.

MATERIAL AND METHODS: To describe this phenomenon a PubMed and national databases were searched for 17β-dehydrotestosterone, common testosterone, free testosterone, 17β-estradiol, luteinizing hormone, partial androgen deficiency of aging men.

RESULTS: The reduction in intensity of the processes of tissue renewal of the testicles results in a partial androgen deficiency of aging men. A decrease in the levels of total and free testosterone and an increase in the levels of 5α-dihydrotestosterone, 17β-estradiol, sex hormone binding globulin, LH and FSH, along with a decrease in the amplitude of the rhythm of incretion of LH, FSH and total testosterone will testify to a deficiency of testosterone.

CONCLUSIONS: It is very important to make an individualized selection of the dose of testosterone preparation which enters the blood plasma.

Keywords: 17β–estradiol; 5α–dehydrotestosterone; common testosterone; free testosterone; luteinizing hormone; partial androgen deficiency of aging men

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