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Epilepsy Behav Case Rep. 2014 Jun 14;2:130-2. doi: 10.1016/j.ebcr.2014.05.003. eCollection 2014.

A case report of a Wada test after dominant hemisphere multiple hippocampal transections: Pathophysiology of confusion after amobarbital injection.

Epilepsy & behavior case reports

Patrick Landazuri, Jonathan Miller, Hans Lüders

Affiliations

  1. University Hospitals, Case Medical Center, Department of Neurology, Epilepsy Division, 11100 Euclid Avenue, Lakeside 3200, Cleveland, OH, USA ; University of Kansas Medical Center, Department of Neurology, 3599 Rainbow Blvd, Kansas City, KS 66103, USA.
  2. University Hospitals, Case Medical Center, Department of Neurosurgery, 11100 Euclid Avenue, Lakeside 3200, Cleveland, OH 44106, USA.
  3. University Hospitals, Case Medical Center, Department of Neurology, Epilepsy Division, 11100 Euclid Avenue, Lakeside 3200, Cleveland, OH, USA.

PMID: 25667890 PMCID: PMC4307959 DOI: 10.1016/j.ebcr.2014.05.003

Abstract

Dialepsis is defined as a predominant alteration of consciousness with preservation of motor tone and the ability to perform movements. While dialepsis is a common feature of both focal and generalized epilepsies, its precise symptomatogenic zone and pathogenesis remain undefined. This case report describes a patient who underwent intracarotid amobarbital procedures before and after dominant hemisphere multiple hippocampal transections. From our observations, we propose a possible pathogenesis for the generation of dialeptic seizures.

Keywords: Dialepsis; Multiple hippocampal transections; Semiology; Symptomatogenic zone; Wada

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