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Eurasian J Med. 2010 Aug;42(2):57-60. doi: 10.5152/eajm.2010.18.

Diffusion-weighted magnetic resonance imaging in evaluation of gastric cancer.

The Eurasian journal of medicine

Mecit Kantarci, Ihsan Yuce, Ahmet Yalcin, M Ilhan Yildirgan, Kerim Cayir, Suat Eren, S Selcuk Atamanalp

Affiliations

  1. Ataturk University, School of Medicine, Department of Radiology, Erzurum, Turkey.
  2. Ataturk University, School of Medicine, Department of General Surgery, Erzurum, Turkey.
  3. Ataturk University, School of Medicine, Department of Medical Oncology, Erzurum, Turkey.

PMID: 25610124 PMCID: PMC4261328 DOI: 10.5152/eajm.2010.18

Abstract

OBJECTIVE: To investigate the role of diffusion-weighted magnetic resonance imaging (DW-MRI) in the diagnosis of gastric tumors and discuss the diagnostic importance and potential use of apparent diffusion coefficient (ADC) measurements.

MATERIALS AND METHODS: Beginning in March 2009, DW-MRI was added to the routine abdominal and pelvic MR examination for all patients imaged at our institution. A total of 21 patients (12 men and 9 women; mean age 55±6.3SD, range: 39-74 years) with known gastric malignancy were referred to our MR unit. All MRI examinations were performed using a 1.5-T MRI scanner (Magnetom Avanto, Siemens Healthcare). The evaluation of the DW-MRI examinations was made by radiologists' consensus. Changes in the signal intensity of the lesions were determined by their appearance in images at b=50, 400, and 800 s/mm(2) and in ADC maps. Results were compared with histopathological findings.

RESULTS: All of the gastric tumors in this study showed high signal intensity in DW-MRI and low signal intensity in ADC maps. Mean ADC values for gastric tumor and normal gastric wall were 0.892±0.23 SD mm(2)/s and 1.453±0.35 SD mm(2)/s respectively. The mean ADC values of gastric tumors were significantly lower than that of the normal gastric wall.

CONCLUSION: DW-MRI and ADC values together can successfully differentiate gastric tumors from normal gastric wall.

Keywords: ADC map; Diffusion Weighted Magnetic Resonance; Gastric Cancer

References

  1. Cancer. 1993 Sep 1;72 (5):1631-6 - PubMed
  2. Radiol Clin North Am. 1997 Mar;35(2):331-49 - PubMed
  3. AJR Am J Roentgenol. 2007 Apr;188(4):1001-8 - PubMed
  4. Radiat Med. 2004 Jul-Aug;22(4):275-82 - PubMed
  5. Magn Reson Med Sci. 2005 Dec 31;4(4):175-86 - PubMed
  6. Eur Radiol. 2007 Jan;17(1):201-4 - PubMed
  7. Radiology. 2006 May;239(2):448-56 - PubMed
  8. Clin Cancer Res. 1997 Sep;3(9):1457-66 - PubMed
  9. AJR Am J Roentgenol. 1999 Aug;173(2):393-8 - PubMed
  10. Radiology. 2004 May;231(2):305-32 - PubMed
  11. AJR Am J Roentgenol. 2007 Feb;188(2):409-14 - PubMed
  12. J Magn Reson Imaging. 2003 Sep;18(3):377-82 - PubMed
  13. Int J Radiat Oncol Biol Phys. 2003 Jul 15;56(4):958-65 - PubMed
  14. Eur Radiol. 2007 Jun;17(6):1385-93 - PubMed
  15. Eur Radiol. 2004 Jun;14(6):959-63 - PubMed
  16. Clin Gastroenterol Hepatol. 2006 Jun;4(6):709-16 - PubMed
  17. Abdom Imaging. 2001 Mar-Apr;26(2):161-5 - PubMed
  18. Radiology. 2006 Jun;239(3):632-49 - PubMed
  19. Radiology. 2002 Jul;224(1):258-64 - PubMed
  20. Magn Reson Med. 2002 Jul;48(1):128-36 - PubMed
  21. Radiology. 1997 Sep;204(3):739-44 - PubMed
  22. Hepatogastroenterology. 2007 Jul-Aug;54(77):1378-81 - PubMed
  23. J Magn Reson Imaging. 2005 Jun;21(6):836-40 - PubMed

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