Display options
Share it on

Case Rep Emerg Med. 2014;2014:321587. doi: 10.1155/2014/321587. Epub 2014 Dec 25.

Acutely onset amiodarone-induced angioedema in a patient with new atrial fibrillation.

Case reports in emergency medicine

Hossein Vakili, Isa Khaheshi, Mehdi Memaryan, Habib Haybar, Shooka Esmaeeli

Affiliations

  1. Cardiovascular Research Center, Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  2. Cardiovascular Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
  3. Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.

PMID: 25610669 PMCID: PMC4291005 DOI: 10.1155/2014/321587

Abstract

A 50-year-old man was admitted to our emergency department due to new episode of palpitation. He had history of angioplasty of right coronary artery (RCA) with drug eluting stent 2 years ago. His electrocardiogram revealed atrial fibrillation (AF). Intravenous amiodarone 150 mg during 10 minutes and then 1 mg/min infusion were started to achieve rate control and pharmacologic conversion to sinus rhythm. After 60 minutes of starting amiodarone infusion, he developed swelling of the skin around his mouth and eyes, and also mucosa of the mouth, eyes and tongue. To conclude, angioedema should be considered a rare side effect of amiodarone which is used broadly in cardiovascular field.

References

  1. J Invest Dermatol. 1989 Aug;93(2):201-9 - PubMed
  2. Allergy. 2000 Dec;55(12):1199-200 - PubMed
  3. Arch Intern Med. 2000 Jun 26;160(12):1741-8 - PubMed
  4. N Engl J Med. 2005 May 5;352(18):1861-72 - PubMed
  5. Am J Cardiol. 2003 Jun 15;91(12):1437-41 - PubMed
  6. N Engl J Med. 2003 Jun 26;348(26):2646-55 - PubMed
  7. Gastroenterology. 2002 Nov;123(5):1705-25 - PubMed
  8. Eur Heart J. 2006 Apr;27(8):949-53 - PubMed
  9. N Engl J Med. 2000 Mar 30;342(13):913-20 - PubMed
  10. Am J Cardiol. 2005 Feb 1;95(3):404-5 - PubMed
  11. Indian J Dermatol Venereol Leprol. 2005 Jan-Feb;71(1):46-7 - PubMed
  12. Am J Cardiol. 2009 Dec 1;104(11):1534-9 - PubMed
  13. Am Heart J. 1985 May;109(5 Pt 1):975-83 - PubMed

Publication Types