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Weiss JM, Wiltout RH. Multifaceted antitumor responses to activating anti-CD40 antibody therapy combined with immunomodulatory or targeted agents. Oncoimmunology. 2014;3(8):e954483doi: 10.4161/21624011.2014.954483.
Weiss, J. M., & Wiltout, R. H. (2014). Multifaceted antitumor responses to activating anti-CD40 antibody therapy combined with immunomodulatory or targeted agents. Oncoimmunology, 3(8), e954483. https://doi.org/10.4161/21624011.2014.954483
Weiss, Jonathan M, and Wiltout, Robert H. "Multifaceted antitumor responses to activating anti-CD40 antibody therapy combined with immunomodulatory or targeted agents." Oncoimmunology vol. 3,8 (2014): e954483. doi: https://doi.org/10.4161/21624011.2014.954483
Weiss JM, Wiltout RH. Multifaceted antitumor responses to activating anti-CD40 antibody therapy combined with immunomodulatory or targeted agents. Oncoimmunology. 2014 Aug 03;3(8):e954483. doi: 10.4161/21624011.2014.954483. eCollection 2014. PMID: 25610748; PMCID: PMC4292511.
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Oncoimmunology. 2014 Aug 03;3(8):e954483. doi: 10.4161/21624011.2014.954483. eCollection 2014.

Multifaceted antitumor responses to activating anti-CD40 antibody therapy combined with immunomodulatory or targeted agents.

Oncoimmunology

Jonathan M Weiss, Robert H Wiltout

Affiliations

  1. Cancer and Inflammation Program; National Cancer Institute ; Frederick, MD USA.

PMID: 25610748 PMCID: PMC4292511 DOI: 10.4161/21624011.2014.954483

Abstract

Therapeutic targeting of the CD40 pathway may be efficacious for cancer treatment. Accumulating evidence suggests synergistic and unique antitumor responses may be achieved using CD40-based therapies in combination with other immunomodulators or targeted agents.

Keywords: biomarkers; immunostimulation; immunotherapy; inflammation; targets; therapeutic antibodies

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