Case Rep Ophthalmol. 2014 Nov 20;5(3):380-5. doi: 10.1159/000369201. eCollection 2014.
Case reports in ophthalmology
Hidenori Sasaki, Takamichi Kokubun
PMID: 25762927 PMCID: PMC4342862 DOI: 10.1159/000369201
A 47-year-old man presented at the Ophthalmology Department of Saku City Asama General Hospital complaining of hyperemia and pain after industrial sodium hydroxide (approx. 40% concentration) had entered his left eye. With an epithelial defect of the bulbar and palpebral conjunctiva, ischemia of the inferior third of the limbal conjunctiva, a total corneal epithelial defect and mild corneal stromal opacity, the damage was determined as Roper-Hall grade III. 2% rebamipide ophthalmic suspension, which is used for dry eye disease, was administered 4 times a day followed by conventional treatment for serious alkali injury. The corneal epithelial defect was resolved, and there were no side effects. The effectiveness of 2% rebamipide ophthalmic suspension in both the repair and improvement of the damage in the conjunctival and corneal epithelia, and its anti-inflammatory effect suggest that it may be an effective treatment not only for dry eye disease but also for alkali ocular damage.
Keywords: 2% rebamipide ophthalmic suspension; Alkali burn; Roper-Hall classification
