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Safaeian L, Mahdanian AR, Salami S, et al. Seasonality and Physician-related Factors Associated with Antibiotic Prescribing: A Cross-sectional Study in Isfahan, Iran. Int J Prev Med. 2015;6:1doi: 10.4103/2008-7802.151431.
Safaeian, L., Mahdanian, A. R., Salami, S., Pakmehr, F., & Mansourian, M. (2015). Seasonality and Physician-related Factors Associated with Antibiotic Prescribing: A Cross-sectional Study in Isfahan, Iran. International journal of preventive medicine, 61. https://doi.org/10.4103/2008-7802.151431
Safaeian, Leila, et al. "Seasonality and Physician-related Factors Associated with Antibiotic Prescribing: A Cross-sectional Study in Isfahan, Iran." International journal of preventive medicine vol. 6 (2015): 1. doi: https://doi.org/10.4103/2008-7802.151431
Safaeian L, Mahdanian AR, Salami S, Pakmehr F, Mansourian M. Seasonality and Physician-related Factors Associated with Antibiotic Prescribing: A Cross-sectional Study in Isfahan, Iran. Int J Prev Med. 2015 Jan 15;6:1. doi: 10.4103/2008-7802.151431. eCollection 2015. PMID: 25789136; PMCID: PMC4362280.
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Int J Prev Med. 2015 Jan 15;6:1. doi: 10.4103/2008-7802.151431. eCollection 2015.

Seasonality and Physician-related Factors Associated with Antibiotic Prescribing: A Cross-sectional Study in Isfahan, Iran.

International journal of preventive medicine

Leila Safaeian, Ali-Reza Mahdanian, Solmaz Salami, Farzaneh Pakmehr, Marjan Mansourian

Affiliations

  1. Department of Pharmacology and Toxicology, Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
  2. Department of Research and Development, Food and Drug Deputy, Isfahan University of Medical Sciences, Isfahan, Iran.
  3. Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

PMID: 25789136 PMCID: PMC4362280 DOI: 10.4103/2008-7802.151431

Abstract

BACKGROUND: Irrational antibiotic prescribing as a global health problem has a major influence on medical care quality and healthcare expenditure. This study was aimed to determine the pattern of antibiotic use and to assess the seasonality and physician-related factors associated with variability in antibiotic prescribing in Isfahan province of Iran.

METHODS: This cross-sectional survey was conducted on all prescriptions issued by general physicians from rural and urban areas in 2011. Associations between season of prescribing and physician-related variables including gender, practice location and time since graduation with antibiotic prescriptions and also the pattern of antibiotic prescribing were assessed using Chi-square tests and multiple logistic regression models.

RESULTS: Of the 7439709 prescriptions issued by 3772 general practitioners, 51% contained at least one antibiotic. Penicillins were the most frequently prescribed antibiotics, followed by cephalosporins and macrolides. Over-prescription of penicillins was associated with female gender (odds ratio [OR], 2.61; 95% confidence interval [CI] 2.13-3.19) and with moderate duration of time in practice (10-20 years) (OR, 1.42; 95% CI 1.14-1.76). Higher rates of cephalosporins prescription were observed in urban areas than rural areas and by male physicians. Seasonal peak was detected for penicillins and cephalosporins prescriptions in autumn.

CONCLUSIONS: These findings showed the widespread use of antibiotics by general practitioners that was associated with the physicians' gender, time since graduation and practice location and also season of prescribing. More researches are needed on other factors related to the overprescribing of antibiotics and they could be used to project educational programs for improvement of antibiotic prescribing quality in our country.

Keywords: Antibiotics; general practice; prescriptions patter; rational drug use

References

  1. Oman Med J. 2011 May;26(3):205-6 - PubMed
  2. BMJ. 2008 Jul 23;337:a437 - PubMed
  3. Ann Pharmacother. 2001 May;35(5):636-40 - PubMed
  4. Can Fam Physician. 1991 Jan;37:72-81 - PubMed
  5. Lancet. 2005 Feb 12-18;365(9459):579-87 - PubMed
  6. Eur J Clin Pharmacol. 2003 Nov;59(8-9):651-7 - PubMed
  7. East Mediterr Health J. 2002 Jul-Sep;8(4-5):550-5 - PubMed
  8. Clin Infect Dis. 1999 Aug;29(2):312-7 - PubMed
  9. Health Policy Plan. 2001 Mar;16(1):13-20 - PubMed
  10. Int J Qual Health Care. 2004 Jun;16(3):245-51 - PubMed
  11. CMAJ. 2007 Oct 9;177(8):895-6 - PubMed
  12. CMAJ. 2007 Oct 9;177(8):877-83 - PubMed
  13. Fam Pract. 1993 Dec;10(4):366-70 - PubMed
  14. Clin Infect Dis. 2012 Sep;55(5):687-94 - PubMed
  15. JAMA. 2003 Feb 12;289(6):719-25 - PubMed
  16. JAMA. 2013 Jun 12;309(22):2345-52 - PubMed
  17. Scand J Prim Health Care. 1998 Jun;16(2):121-7 - PubMed
  18. BMJ. 2007 Sep 1;335(7617):407-8 - PubMed
  19. Iran J Pharm Res. 2013 Winter;12(1):235-41 - PubMed
  20. EXCLI J. 2013 May 07;12:384-95 - PubMed
  21. Pak J Biol Sci. 2012 Jul 15;15(14):707-8 - PubMed
  22. J Clin Pharm Ther. 2008 Dec;33(6):625-34 - PubMed
  23. Fam Pract. 2005 Apr;22(2):160-7 - PubMed
  24. Qual Saf Health Care. 2007 Dec;16(6):440-5 - PubMed
  25. J Gen Intern Med. 2005 Aug;20(8):697-702 - PubMed
  26. Bull World Health Organ. 2001;79(4):313-20 - PubMed
  27. Emerg Infect Dis. 2002 Dec;8(12):1460-7 - PubMed
  28. Ambul Pediatr. 2006 Jul-Aug;6(4):225-9 - PubMed
  29. East Mediterr Health J. 2011 Oct;17(10):763-9 - PubMed
  30. J Antimicrob Chemother. 2008 Aug;62(2):410-5 - PubMed
  31. Scand J Infect Dis. 2011 Jul;43(6-7):479-88 - PubMed
  32. BMJ. 2009 Jun 23;338:b2242 - PubMed
  33. J Microbiol Immunol Infect. 2003 Sep;36(3):182-6 - PubMed

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