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Raynaud CM, Ahmad FS, Allouba M, et al. Reprogramming for cardiac regeneration. Glob Cardiol Sci Pract. 2014;2014(3):309-29doi: 10.5339/gcsp.2014.44.
Raynaud, C. M., Ahmad, F. S., Allouba, M., Abou-Saleh, H., Lui, K. O., & Yacoub, M. (2014). Reprogramming for cardiac regeneration. Global cardiology science & practice, 2014(3), 309-29. https://doi.org/10.5339/gcsp.2014.44
Raynaud, Christophe Michel, et al. "Reprogramming for cardiac regeneration." Global cardiology science & practice vol. 2014,3 (2014): 309-29. doi: https://doi.org/10.5339/gcsp.2014.44
Raynaud CM, Ahmad FS, Allouba M, Abou-Saleh H, Lui KO, Yacoub M. Reprogramming for cardiac regeneration. Glob Cardiol Sci Pract. 2014 Oct 16;2014(3):309-29. doi: 10.5339/gcsp.2014.44. eCollection 2014. PMID: 25763379; PMCID: PMC4352683.
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Glob Cardiol Sci Pract. 2014 Oct 16;2014(3):309-29. doi: 10.5339/gcsp.2014.44. eCollection 2014.

Reprogramming for cardiac regeneration.

Global cardiology science & practice

Christophe Michel Raynaud, Faizzan Syed Ahmad, Mona Allouba, Haissam Abou-Saleh, Kathy O Lui, Magdi Yacoub

Affiliations

  1. Qatar Cardiovascular Research Center, Qatar Foundation-Education City, Doha, Qatar.
  2. Aswan Heart Center, Magdi Yacoub Foundation, Aswan, Egypt.
  3. Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, USA.

PMID: 25763379 PMCID: PMC4352683 DOI: 10.5339/gcsp.2014.44

Abstract

Treatment of cardiovascular diseases remains challenging considering the limited regeneration capacity of the heart muscle. Developments of reprogramming strategies to create in vitro and in vivo cardiomyocytes have been the focus point of a considerable amount of research in the past decades. The choice of cells to employ, the state-of-the-art methods for different reprogramming strategies, and their promises and future challenges before clinical entry, are all discussed here.

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