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Front Neurol. 2015 Jan 28;5:286. doi: 10.3389/fneur.2014.00286. eCollection 2014.

Management of super-refractory status epilepticus with isoflurane and hypothermia.

Frontiers in neurology

Agzam Zhumadilov, Charles P Gilman, Dmitriy Viderman

Affiliations

  1. Republican Research Center for Emergency Care , Astana , Kazakhstan.
  2. School of Science and Technology, Nazarbayev University , Astana , Kazakhstan.
  3. Republican Research Center for Emergency Care , Astana , Kazakhstan ; School of Medicine, Nazarbayev University , Astana , Kazakhstan.

PMID: 25674075 PMCID: PMC4309114 DOI: 10.3389/fneur.2014.00286

Abstract

Super-refractory status epilepticus (SRSE) is defined as status epilepticus that continues 24 h or more after the onset of anesthesia, and includes those cases in which epilepsy is recurrent upon treatment reduction. We describe the presentation and successful management of a male patient with SRSE using the inhaled anesthetic isoflurane, and mild hypothermia (HT). The potential utility of combined HT and volatile anesthesia is discussed.

Keywords: SRSE; epilepsy; hypothermia; isoflurane; neurocritical care; neurotrauma

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