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Springerplus. 2014 Dec 13;3:731. doi: 10.1186/2193-1801-3-731. eCollection 2014.

A poor prognostic case of peripheral T-cell lymphoma in the base of tongue with chemotherapy followed by radiation therapy.

SpringerPlus

Jun-Ho Lee, Seok Ho Lee

Affiliations

  1. Department of Emergency Medical Technology, Daejeon University, 62 Daehak-ro, Dong-gu, Daejeon, 300-716 Korea.
  2. Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760 Korea.

PMID: 25674463 PMCID: PMC4320182 DOI: 10.1186/2193-1801-3-731

Abstract

A 59-year old male had odynophagia and globus sensation for 10 days prior to his visit. Endoscopically, a fungating mass was observed in the right side of the tongue base (BOT). The peripheral T-cell lymphoma (PTCL) was confirmed by a punch biopsy. The patient was classified as stage IIA according to the Ann Arbor staging classification. Radiation therapy (RT) using volumetric modulated arc therapy (VAMT) began after 8 cycles of CHOP chemotherapy. Although the patient achieved a complete remission without RT relating morbidity during the follow-up period, recurrence occurred in the right orbit at 3 months after treatment. The patient received RT with high energy electron on the right orbit. The salvage chemotherapy was followed by RT. The patient died of aggravation of PTCL at 17 months after VMAT. We report a poor prognostic case of PTCL in BOT with chemotherapy followed by RT.

Keywords: Base of tongue; Peripheral T cell lymphoma; Radiation Therapy

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