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Clin Case Rep. 2014 Oct;2(5):206-8. doi: 10.1002/ccr3.95. Epub 2014 Jul 25.

Pulmonary squamous cell carcinoma and sorafenib.

Clinical case reports

Russell Gollard, Diana Garcia, Ron Natale

Affiliations

  1. Cancer & Blood Specialists of Nevada 2460 W. Horizon Ridge Pkwy., Henderson, Nevada, 89052.
  2. Quest Diagnostics 4230 Burnham Ave., Las Vegas, Nevada, 89119.
  3. Cedars-Sinai Comprehensive Cancer Center 8700 Beverly Blvd, Suite AC10, West Hollywood, California, 90048.

PMID: 25614813 PMCID: PMC4302627 DOI: 10.1002/ccr3.95

Abstract

KEY CLINICAL MESSAGE: Pulmonary squamous cell carcinomas are not often thought to sensitive to targeted agents, like their cousin the adenocarcinoma of the lung. With appropriate testing of molecular markers, squamous cell carcinomas, like adenocarcinomas of the lung, melanomas, and renal cell carcinomas, may be found to be sensitive to newer, targeted agents.

Keywords: BRAF mutants; nonsmall cell lung cancer; squamous cell carcinoma; targeted therapy

References

  1. J Clin Oncol. 2012 Mar 10;30(8):863-70 - PubMed
  2. Oncologist. 2013;18(2):115-22 - PubMed
  3. Clin Lung Cancer. 2012 Sep;13(5):391-5 - PubMed
  4. J Thorac Oncol. 2011 Jul;6(7):1260-6 - PubMed
  5. Nature. 2002 Jun 27;417(6892):949-54 - PubMed
  6. J Clin Oncol. 2010 Apr 10;28(11):1835-42 - PubMed
  7. Cancer Res. 2002 Dec 1;62(23):6997-7000 - PubMed
  8. Science. 2004 Jun 4;304(5676):1497-500 - PubMed
  9. J Clin Oncol. 2010 Nov 1;28(31):4769-77 - PubMed
  10. Proc Natl Acad Sci U S A. 2012 Jul 31;109 (31):E2127-33 - PubMed
  11. J Clin Oncol. 2012 Jun 10;30(17 ):2070-8 - PubMed
  12. J Clin Oncol. 2012 Feb 20;30(6):647-60 - PubMed
  13. Nat Med. 2011 Nov 13;17(12):1641-5 - PubMed
  14. Oncogene. 2009 Jan 8;28(1):85-94 - PubMed
  15. J Clin Oncol. 2005 May 10;23(14):3219-26 - PubMed

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