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Indian J Pharm Sci. 2015 Jan-Feb;77(1):41-8. doi: 10.4103/0250-474x.151596.

In vitro Antioxidant Potential in Sequential Extracts of Curcuma caesia Roxb. Rhizomes.

Indian journal of pharmaceutical sciences

J Reenu, Shamina Azeez, Chempakam Bhageerathy

Affiliations

  1. Indian Institute of Spices Research, Marikunnu P.O., Kozhikode-673 012, India.

PMID: 25767317 PMCID: PMC4355881 DOI: 10.4103/0250-474x.151596

Abstract

Present study deals with antioxidant potential of sequential extracts of fresh and dried rhizomes of Curcuma caesia, using solvents viz., hexane, petroleum ether, benzene, chloroform, ethyl acetate, methanol and water, which was analyzed by 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay, total antioxidant capacity, ferric reducing activity and thiobarbituric acid reactive species assay. Total phenol content was estimated by the Folin-Ciocalteau method. C. caesia showed significant antioxidant activity in chloroform, benzene and ethyl acetate extracts. The chloroform extract was highly effective as free radical scavengers, electron-donating agents and reducing molybdate ions except for reducing lipid peroxidation. The highest total phenol content was also exhibited by chloroform and benzene extracts. Antioxidant potential expressed by C. caesia in the sequential extracts could be effectively utilized for identification of the bioactive compounds for future phytopharmacological applications.

Keywords: Curcuma caesia; antioxidants; reactive oxygen species; total phenols

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