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Verma D, Puri V, Agarwal S, et al. Primary thyroid lymphoma: A rare disease. J Cytol. 2014;31(4):218-20doi: 10.4103/0970-9371.151139.
Verma, D., Puri, V., Agarwal, S., & Bhaskar, A. (2014). Primary thyroid lymphoma: A rare disease. Journal of cytology, 31(4), 218-20. https://doi.org/10.4103/0970-9371.151139
Verma, Deepti, et al. "Primary thyroid lymphoma: A rare disease." Journal of cytology vol. 31,4 (2014): 218-20. doi: https://doi.org/10.4103/0970-9371.151139
Verma D, Puri V, Agarwal S, Bhaskar A. Primary thyroid lymphoma: A rare disease. J Cytol. 2014 Oct-Dec;31(4):218-20. doi: 10.4103/0970-9371.151139. PMID: 25745292; PMCID: PMC4349017.
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J Cytol. 2014 Oct-Dec;31(4):218-20. doi: 10.4103/0970-9371.151139.

Primary thyroid lymphoma: A rare disease.

Journal of cytology

Deepti Verma, Vandana Puri, Shilpi Agarwal, Aasha Bhaskar

Affiliations

  1. Department of Pathology, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, New Delhi, India.

PMID: 25745292 PMCID: PMC4349017 DOI: 10.4103/0970-9371.151139

Abstract

Primary thyroid lymphomas are rare neoplasms comprising of 1-5% of thyroid malignancies. These are predominantly B-cell in origin. Here, we report a case of 60 years lady, a known case of lymphocytic thyroiditis, diagnosed as thyroid lymphoma (diffuse large B-cell) on fine needle aspiration and confirmed histopathogically and immunohistochemically. She presented with a sudden increase in thyroid swelling. Fine needle aspiration performed showed highly cellular smears comprising predominantly of the monomorphic population of medium to large sized lymphoid cells with high nuclear/cytoplasmic ratio and scant cytoplasm. A possibility of thyroid lymphoma possibly diffuse large B-cell lymphoma was suggested which was later confirmed on biopsy. Fine needle aspiration provides an easy mode for diagnosing large cell lymphoma like diffuse large B-cell. Hence, an early diagnosis is possible for a timely intervention. Also, cases of lymphocytic thyroiditis should be regularly followed for the development of lymphoma.

Keywords: Lymphoma; fine needle aspiration cytology; primary; thyroid; thyroiditis

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