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Brusca N, Del Duca SC, Salvatori R, et al. A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid: is conservative treatment always advised?. Int J Endocrinol Metab. 2015;13(1):e18220doi: 10.5812/ijem.18220.
Brusca, N., Del Duca, S. C., Salvatori, R., D'Agostini, A., Cannas, P., Santaguida, M. G., Virili, C., Bianchi, L., Gargano, L., & Centanni, M. (2015). A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid: is conservative treatment always advised?. International journal of endocrinology and metabolism, 13(1), e18220. https://doi.org/10.5812/ijem.18220
Brusca, Nunzia, et al. "A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid: is conservative treatment always advised?." International journal of endocrinology and metabolism vol. 13,1 (2015): e18220. doi: https://doi.org/10.5812/ijem.18220
Brusca N, Del Duca SC, Salvatori R, D'Agostini A, Cannas P, Santaguida MG, Virili C, Bianchi L, Gargano L, Centanni M. A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid: is conservative treatment always advised?. Int J Endocrinol Metab. 2015 Jan 22;13(1):e18220. doi: 10.5812/ijem.18220. eCollection 2015 Jan. PMID: 25745492; PMCID: PMC4338667.
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Int J Endocrinol Metab. 2015 Jan 22;13(1):e18220. doi: 10.5812/ijem.18220. eCollection 2015 Jan.

A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid: is conservative treatment always advised?.

International journal of endocrinology and metabolism

Nunzia Brusca, Susanna Carlotta Del Duca, Rita Salvatori, Antonio D'Agostini, Pina Cannas, Maria Giulia Santaguida, Camilla Virili, Loredana Bianchi, Lucilla Gargano, Marco Centanni

Affiliations

  1. Department of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Latina, Italy.
  2. Department of Nuclear Medicine, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
  3. Endocrinology Unit, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
  4. Department of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Latina, Italy ; Endocrinology Unit, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.

PMID: 25745492 PMCID: PMC4338667 DOI: 10.5812/ijem.18220

Abstract

INTRODUCTION: Struma ovarii is an ovarian teratoma, represented in more than 50% by thyroid tissue. Five percent of struma ovarii cases have been proven to be malignant and, as in the thyroid gland, papillary thyroid carcinoma is the most common histotype arising in struma ovarii. Because of the unusual occurrence of this tumor, its management and follow-up after pelvic surgery is still controversial. Usually, total thyroidectomy followed by radioiodine treatment is the choice treatment in metastatic malignant struma ovarii, while these procedures are still controversial in non-metastatic thyroid cancer arising in struma ovarii.

CASE PRESENTATION: We report a female with follicular variant of papillary thyroid carcinoma arising in struma ovarii. After pelvic surgery, thyroid morphofunctional examinations were performed and a single nodular lesion in the left lobe was discovered. The patient underwent total thyroidectomy and histological examination showed a papillary carcinoma. Radioiodine-ablation of residual thyroid tissue was performed and levothyroxine mildly-suppressive treatment was started.

CONCLUSIONS: A more aggressive treatment should not be denied for malignant struma ovarii without any evidence, even when apparently confined into the ovary. However, in selected cases, aggressive treatment may be advisable to decrease the risk of recurrence and to allow an accurate follow-up.

Keywords: Struma Ovarii; Thyroid Carcinoma; Thyroidectomy

References

  1. Endocr Pract. 2012 Jan-Feb;18(1):e1-4 - PubMed
  2. Thyroid. 2012 Apr;22(4):400-6 - PubMed
  3. Arch Pathol Lab Med. 2010 May;134(5):786-91 - PubMed
  4. Pathol Oncol Res. 2002;8(2):145-7 - PubMed
  5. Clin Nucl Med. 2013 Jan;38(1):25-8 - PubMed
  6. Cancer Treat Rev. 2005 Oct;31(6):423-38 - PubMed
  7. Thyroid. 2009 Nov;19(11):1167-214 - PubMed
  8. Thyroid. 2013 Aug;23(8):1042-3 - PubMed
  9. BMJ Case Rep. 2012 Jul 11;2012:null - PubMed
  10. Gynecol Obstet Invest. 2008;65(2):104-7 - PubMed
  11. Eur J Endocrinol. 2006 Jun;154(6):787-803 - PubMed
  12. J Gynecol Oncol. 2008 Jun;19(2):135-8 - PubMed
  13. Am J Clin Pathol. 2009 Nov;132(5):658-65 - PubMed
  14. J Obstet Gynaecol. 2012 Apr;32(3):222-6 - PubMed
  15. Clin Med Oncol. 2008;2:147-52 - PubMed
  16. Patholog Res Int. 2010 Aug 02;2010:352476 - PubMed
  17. Endocr Pathol. 2010 Jun;21(2):144-7 - PubMed
  18. Endocr Pract. 2009 Mar;15(2):167-73 - PubMed
  19. J Exp Clin Cancer Res. 1997 Sep;16(3):337-47 - PubMed
  20. J Clin Imaging Sci. 2011;1:44 - PubMed

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