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Kalra S, Gupta Y. Injectable Coformulations in Diabetology. Diabetes Ther. 2015;6(2):101-11doi: 10.1007/s13300-015-0106-2.
Kalra, S., & Gupta, Y. (2015). Injectable Coformulations in Diabetology. Diabetes therapy : research, treatment and education of diabetes and related disorders, 6(2), 101-11. https://doi.org/10.1007/s13300-015-0106-2
Kalra, Sanjay, and Gupta, Yashdeep. "Injectable Coformulations in Diabetology." Diabetes therapy : research, treatment and education of diabetes and related disorders vol. 6,2 (2015): 101-11. doi: https://doi.org/10.1007/s13300-015-0106-2
Kalra S, Gupta Y. Injectable Coformulations in Diabetology. Diabetes Ther. 2015 Jun;6(2):101-11. doi: 10.1007/s13300-015-0106-2. Epub 2015 Mar 24. PMID: 25801349; PMCID: PMC4478180.
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Diabetes Ther. 2015 Jun;6(2):101-11. doi: 10.1007/s13300-015-0106-2. Epub 2015 Mar 24.

Injectable Coformulations in Diabetology.

Diabetes therapy : research, treatment and education of diabetes and related disorders

Sanjay Kalra, Yashdeep Gupta

Affiliations

  1. Bharti Hospital and B.R.I.D.E, Karnal, Haryana, 132001, India, [email protected].

PMID: 25801349 PMCID: PMC4478180 DOI: 10.1007/s13300-015-0106-2

Abstract

Coformulations are a novel pharmaceutical development in diabetology. They are composed of two medicinal products, both of which maintain their distinct pharmacokinetic and pharmacodynamic properties. Currently available coformulations include combinations of basal and rapid-acting insulin, and basal and glucagon-like peptide 1 receptor agonists (GLP1RA). This review describes three coformulations which are in advanced stages of development, or are approved in certain markets. We discuss the basic and clinical pharmacology of these drugs, while describing clinical usage of the commercially available insulin degludec aspart (IDegAsp).

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