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Int J Stroke. 2015 Jul;10(5):659-64. doi: 10.1111/ijs.12490. Epub 2015 Apr 06.

7 Tesla MRI in cerebral small vessel disease.

International journal of stroke : official journal of the International Stroke Society

Philip Benjamin, Olivia Viessmann, Andrew D MacKinnon, Peter Jezzard, Hugh S Markus

Affiliations

  1. Neurosciences Research Centre, St George's University of London, London, UK.
  2. Functional MRI of the Brain (FMRIB) Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
  3. Atkinson Morley Regional Neuroscience Centre, St George's NHS Healthcare Trust, London, UK.
  4. Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

PMID: 25845965 DOI: 10.1111/ijs.12490

Abstract

Cerebral small vessel disease (SVD) is a major cause of stroke and cognitive decline. Magnetic resonance imaging (MRI) currently plays a central role in diagnosis, and advanced MRI techniques are widely used in research but are limited by spatial resolution. Human 7 Tesla (7T) MRI has recently become available offering the ability to image at higher spatial resolution. This may provide additional insights into both the vascular pathology itself as well as parenchymal markers which could only previously be examined post mortem. In this review we cover the advantages and limitations of 7T MRI, review studies in SVD performed to date, and discuss potential future insights into SVD which 7T MRI may provide.

© 2015 World Stroke Organization.

Keywords: : 7T MRI; small vessel disease

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