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Dudani S, Malik A, Sandhu AS, et al. Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate. Indian J Urol. 2015;31(2):136-8doi: 10.4103/0970-1591.152921.
Dudani, S., Malik, A., Sandhu, A. S., & Mani, N. S. (2015). Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate. Indian journal of urology : IJU : journal of the Urological Society of India, 31(2), 136-8. https://doi.org/10.4103/0970-1591.152921
Dudani, Sharmila, et al. "Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate." Indian journal of urology : IJU : journal of the Urological Society of India vol. 31,2 (2015): 136-8. doi: https://doi.org/10.4103/0970-1591.152921
Dudani S, Malik A, Sandhu AS, Mani NS. Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate. Indian J Urol. 2015 Apr-Jun;31(2):136-8. doi: 10.4103/0970-1591.152921. PMID: 25878416; PMCID: PMC4397551.
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Indian J Urol. 2015 Apr-Jun;31(2):136-8. doi: 10.4103/0970-1591.152921.

Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate.

Indian journal of urology : IJU : journal of the Urological Society of India

Sharmila Dudani, Ajay Malik, A S Sandhu, N S Mani

Affiliations

  1. Department of Pathology, Army College of Medical Sciences and Base Hospital, Delhi Cantt, Delhi, India.
  2. Department of Urology, Army College of Medical Sciences and Base Hospital, Delhi Cantt, Delhi, India.

PMID: 25878416 PMCID: PMC4397551 DOI: 10.4103/0970-1591.152921

Abstract

Carcinosarcoma (CS) or Sarcomatoid carcinoma (SC) of the prostate is a very rare malignant tumor of the prostate having an aggressive clinical course and dismal prognosis. The adenocarcinomatous element is usually of the acinar type and closely admixed with a sarcomatous component. We report a case of α-methyl-CoA-racemase (AMACR)-negative pseudohyperplastic variant of adenocarcinoma in CS. To the best of our knowledge, there have been no published case reports of this variant in CS till date. An accurate diagnosis is essential as this uncommon, aggressive cancer has limited therapeutic options.

Keywords: carcinosarcoma prostate; pseudohyperplastic variant; α-methyl–CoA-racemase

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