Display options
Cite
Amraie H, Shakib P, Rouhi S, et al. Prevalence assessment of magA gene and antimicrobial susceptibility of Klebsiella pneumoniae isolated from clinical specimens in Shahrekord, Iran. Iran J Microbiol. 2014;6(5):311-6
Amraie, H., Shakib, P., Rouhi, S., Bakhshandeh, N., & Zamanzad, B. (2014). Prevalence assessment of magA gene and antimicrobial susceptibility of Klebsiella pneumoniae isolated from clinical specimens in Shahrekord, Iran. Iranian journal of microbiology, 6(5), 311-6.
Amraie, Hadis, et al. "Prevalence assessment of magA gene and antimicrobial susceptibility of Klebsiella pneumoniae isolated from clinical specimens in Shahrekord, Iran." Iranian journal of microbiology vol. 6,5 (2014): 311-6.
Amraie H, Shakib P, Rouhi S, Bakhshandeh N, Zamanzad B. Prevalence assessment of magA gene and antimicrobial susceptibility of Klebsiella pneumoniae isolated from clinical specimens in Shahrekord, Iran. Iran J Microbiol. 2014 Oct;6(5):311-6. PMID: 25848520; PMCID: PMC4385570.
Copy Download .nbib Format: NLM
Share it on

Iran J Microbiol. 2014 Oct;6(5):311-6.

Prevalence assessment of magA gene and antimicrobial susceptibility of Klebsiella pneumoniae isolated from clinical specimens in Shahrekord, Iran.

Iranian journal of microbiology

Hadis Amraie, Pegah Shakib, Samaneh Rouhi, Neda Bakhshandeh, Behnam Zamanzad

Affiliations

  1. Department of Microbiology, Lorestan University of Medical Sciences, Khorramabad, Iran.
  2. Cellular & Molecular Research Center and Microbiology Department, Member of Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.
  3. Applied Agriculture Branch, Semnan Applied Sciences and Technology University, Semnan, Iran.
  4. Department of Microbiology, Shahrekord University of Medical Sciences, ShahreKord, Iran.

PMID: 25848520 PMCID: PMC4385570

Abstract

BACKGROUND AND OBJECTIVES: Klebsiella pneumoniae (K. pneumoniae) is an opportunistic microorganism. This study aimed to investigate the presence of magA gene and antimicrobial susceptibility in K. pneumoniae.

MATERIALS AND METHODS: clinical specimens were collected from hospitals of Shahrekord, Iran. Bacterial culture, biochemical diagnostic standard test, determination of antibiotic sensitivity, phenotypic testing hypermucoviscosity (HV) and polymerase chain reaction (PCR) was performed for isolation and characterization of K. pneumoniae.

RESULTS: 173 samples were positive for K. pneumoniae. The highest and lowest rates of resistance were related to amoxicillin 79.19% and ciprofloxacin 15.60%, respectively. Also 4 samples were positive for magA gene.

CONCLUSION: Based on our results, K. pneumoniae strains were resistant to different antibiotics. Knowing how to identify strains of K. pneumoniae, spreading of its virulence and also antimicrobial resistance genes can be useful in treatment of infection caused by this bacterium.

Keywords: Klebsiella pneumoniae; antimicrobial susceptibility; magA gene; prevalence

References

  1. Antimicrob Agents Chemother. 2011 Sep;55(9):4267-76 - PubMed
  2. J Clin Microbiol. 2007 Feb;45(2):466-71 - PubMed
  3. J Med Microbiol. 2005 Nov;54(Pt 11):1111-3 - PubMed
  4. Jpn J Infect Dis. 2005 Dec;58(6):366-8 - PubMed
  5. Clin Infect Dis. 2006 May 15;42(10):1351-8 - PubMed
  6. Lett Appl Microbiol. 2010 Jul;51(1):65-74 - PubMed
  7. Iran J Microbiol. 2011 Mar;3(1):26-30 - PubMed
  8. Clin Microbiol Rev. 1998 Oct;11(4):589-603 - PubMed
  9. Iran J Basic Med Sci. 2013 Feb;16(2):173-6 - PubMed
  10. J Infect. 2007 Jun;54(6):578-83 - PubMed
  11. Chin Med J (Engl). 2007 Jan 20;120(2):136-9 - PubMed
  12. Ethiop J Health Sci. 2011 Jul;21(2):141-6 - PubMed
  13. Int J Hyg Environ Health. 2006 Nov;209(6):521-6 - PubMed
  14. J Bacteriol. 2005 Jun;187(12):4198-206 - PubMed
  15. Infection. 2010 Dec;38(6):459-64 - PubMed
  16. Appl Microbiol. 1975 Jun;29(6):819-25 - PubMed
  17. J Clin Microbiol. 2005 Feb;43(2):991-2 - PubMed
  18. J Exp Med. 2004 Mar 1;199(5):697-705 - PubMed
  19. J Bacteriol. 2009 Mar;191(6):1941-50 - PubMed
  20. J Clin Microbiol. 1997 Sep;35(9):2370-4 - PubMed

Publication Types