Pak J Med Sci. 2015 Jan-Feb;31(1):116-20. doi: 10.12669/pjms.311.6292.
Corneal topography analysis of stromal corneal dystrophies.
Pakistan journal of medical sciences
Yusuf Kocluk, Zuleyha Yalniz-Akkaya, Ayse Burcu, Firdevs Ornek
Affiliations
Affiliations
- Yusuf Kocluk, MD, Ophthalmolgy Clinic, Ministry of Health, Adana Numune Training and Research Hospital, TR01076, Adana, Turkey.
- Zuleyha Yalniz-Akkaya, MD, Ophthalmolgy Clinic, Ministry of Health, Ankara Training and Research Hospital, TR06340 Ankara, Turkey.
- Ayse Burcu, Associate Professor, Ophthalmolgy Clinic, Ministry of Health, Ankara Training and Research Hospital, TR06340 Ankara, Turkey.
- Firdevs Ornek, MD, Ophthalmolgy Clinic, Ministry of Health, Ankara Training and Research Hospital, TR06340 Ankara, Turkey.
PMID: 25878626
PMCID: PMC4386169 DOI: 10.12669/pjms.311.6292
Abstract
OBJECTIVE: The aim was to compare the corneal topography and tomography parameters of macular corneal dystrophy (MCD), granular corneal dystrophy (GCD) and lattice corneal dystrophy (LCD) patients obtained by Scheimpflug imaging system.
METHODS: The charts, photographs and topography images of patients were reviewed retrospectively. This study included 73 eyes of 73 patients (28 MCD, 20 GCG and 25 LCD patients). Topography images were obtained by Pentacam (Oculus Optikgerate, Wetzlar, Germany). The densitometry readings at the corneal apex were used for the statistics.
RESULTS: The female to male ratio was 13/15 in MCD group, 12/8 in GCD group and 13/12 in LCD group. The mean age median age was 32, 45 and 53 years in MCD, GCD and LCD groups respectively. The groups were similar regarding the gender (p=0.861). The MCD group was significantly younger than the other two groups (p<0.001). The median (minmum-maximum) corneal densities were 100 (100-100), 68 (17-100) and 97 (34-100) Pentacam densitometry units in MCD, GCD and LCD groups respectively. The corneal density at the corneal apex was significantly higher in MCD group than in the other groups (p<0.001). The GCD and LCD groups were statistically similar in terms of density of the corneal apex (p=0.079). In MCD group, corneal thickness at the apex and at the thinnest location was significantly thinner, than in the other groups (p=.002 for thickness at apex between MCD and LCD, and p<.001 for all the remaining comparisons). In MCD group corneal volume was significantly smaller than in the other groups (p<.001 for all comparisons).
CONCLUSION: Densitometry on Scheimpflug imaging system gives information on the density of corneal opacities.
Keywords: Granular corneal dystrophy; Lattice corneal dystrophy; Macular corneal dystrophy; Pentacam corneal densitometry unit; Scheimpflug imaging
References
- Curr Opin Ophthalmol. 2007 Jul;18(4):325-33 - PubMed
- Oman J Ophthalmol. 2009 May;2(2):79-81 - PubMed
- Int J Ophthalmol. 2013 Aug 18;6(4):510-4 - PubMed
- Curr Eye Res. 1990 Apr;9(4):393-8 - PubMed
- Cornea. 2004 Jul;23(5):508-12 - PubMed
- Am J Ophthalmol. 1986 Jan 15;101(1):112-3 - PubMed
- Klin Monbl Augenheilkd. 1984 Sep;185(3):167-73 - PubMed
- Trans Ophthalmol Soc U K. 1966;86:367-416 - PubMed
- Orphanet J Rare Dis. 2009 Feb 23;4:7 - PubMed
- Ophthalmology. 2008 Sep;115(9):1534-9 - PubMed
- Acta Ophthalmol (Copenh). 1978 Jun;56(3):412-6 - PubMed
Publication Types