Display options
Cite
Kianpour M, Norozi S, Bahadoran P, et al. The relationship between metabolic syndrome criteria and preeclampsia in primigravid women. Iran J Nurs Midwifery Res. 2015;20(2):263-8
Kianpour, M., Norozi, S., Bahadoran, P., & Azadbakht, L. (2015). The relationship between metabolic syndrome criteria and preeclampsia in primigravid women. Iranian journal of nursing and midwifery research, 20(2), 263-8.
Kianpour, Maryam, et al. "The relationship between metabolic syndrome criteria and preeclampsia in primigravid women." Iranian journal of nursing and midwifery research vol. 20,2 (2015): 263-8.
Kianpour M, Norozi S, Bahadoran P, Azadbakht L. The relationship between metabolic syndrome criteria and preeclampsia in primigravid women. Iran J Nurs Midwifery Res. 2015 Mar-Apr;20(2):263-8. PMID: 25878706; PMCID: PMC4387653.
Copy Download .nbib Format: NLM
Share it on

Iran J Nurs Midwifery Res. 2015 Mar-Apr;20(2):263-8.

The relationship between metabolic syndrome criteria and preeclampsia in primigravid women.

Iranian journal of nursing and midwifery research

Maryam Kianpour, Shahla Norozi, Parvin Bahadoran, Leila Azadbakht

Affiliations

  1. Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.
  2. Department of Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran.

PMID: 25878706 PMCID: PMC4387653

Abstract

BACKGROUND: Pregnancy is associated with many physiological changes, which in some cases may cause serious risks such as preeclampsia, and fetal and maternal health threats. Recent research has focused on the relationship between metabolic syndrome and preeclampsia. By identifying appropriate indicators for early diagnosis, maternal-fetal complications can be prevented. The present study aimed to investigate the association between metabolic syndrome indicators and the occurrence of preeclampsia in nulliparous pregnant women.

MATERIALS AND METHODS: This was a prospective cohort study conducted on 220 nulliparous pregnant women (normal metabolic syndrome) from Isfahan health centers, Iran, selected by random quota sampling method. With physical examination and laboratory results, metabolic syndrome and preeclampsia in the second half of pregnancy were identified. Data analysis was performed using SPSS software. Descriptive statistical tests were used for demographic characteristics, and Chi-square test, Student's independent t-test, and Fisher's exact test were used to determine and compare the prevalence of metabolic syndrome indicators and preeclampsia.

RESULTS: The relative frequencies of preeclampsia in the group of pregnant women with metabolic syndrome and the healthy group before week 30 (P < 0.001) and after 30 weeks of pregnancy (P < 0.001) were significantly different. The results showed a significant difference in the mean triglycerides and fasting plasma glucose between preeclampsia and control groups; however, the mean high density lipoprotein (HDL) in both groups had no significant differences.

CONCLUSIONS: Based on the results of this study, it was found that in subjects with the metabolic syndrome during pregnancy, the risk for preeclampsia in the second half of pregnancy was higher than in the general population. In this respect, with the design of preventive programs, such as weight management and lowering harmful blood lipids, this complication in pregnancy can be prevented to some extent, or its serious complications can be decreased by early diagnosis. Controlling these indicators before pregnancy as preconception care for individuals at high risk of preeclampsia is recommended.

Keywords: Body mass index; Iran; metabolic syndrome; preeclampsia; prenatal care

References

  1. Am J Obstet Gynecol. 2007 Oct;197(4):411.e1-5 - PubMed
  2. Diabetes Care. 2001 Sep;24(9):1629-33 - PubMed
  3. Ann Epidemiol. 2005 Aug;15(7):475-82 - PubMed
  4. BMJ. 2002 Jul 20;325(7356):157-60 - PubMed
  5. BJOG. 2003 Apr;110(4):400-4 - PubMed
  6. Diabetes Care. 2003 Nov;26(11):3153-9 - PubMed
  7. Arch Gynecol Obstet. 2009 Dec;280(6):921-4 - PubMed
  8. BJOG. 2006 Apr;113(4):379-86 - PubMed
  9. JAMA. 2001 May 16;285(19):2486-97 - PubMed
  10. Hypertension. 2006 Mar;47(3):449-53 - PubMed
  11. Obstet Gynecol. 2005 Jun;105(6):1373-80 - PubMed
  12. Appl Physiol Nutr Metab. 2007 Feb;32(1):76-88 - PubMed
  13. Am J Obstet Gynecol. 2000 Feb;182(2):364-9 - PubMed
  14. Am J Obstet Gynecol. 2000 Aug;183(2):444-8 - PubMed

Publication Types