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Assogba K, Balaka B, Touglo FA, et al. Febrile seizures in one-five aged infants in tropical practice: Frequency, etiology and outcome of hospitalization. J Pediatr Neurosci. 2015;10(1):9-12doi: 10.4103/1817-1745.154315.
Assogba, K., Balaka, B., Touglo, F. A., Apetsè, K. M., & Kombaté, D. (2015). Febrile seizures in one-five aged infants in tropical practice: Frequency, etiology and outcome of hospitalization. Journal of pediatric neurosciences, 10(1), 9-12. https://doi.org/10.4103/1817-1745.154315
Assogba, Komi, et al. "Febrile seizures in one-five aged infants in tropical practice: Frequency, etiology and outcome of hospitalization." Journal of pediatric neurosciences vol. 10,1 (2015): 9-12. doi: https://doi.org/10.4103/1817-1745.154315
Assogba K, Balaka B, Touglo FA, Apetsè KM, Kombaté D. Febrile seizures in one-five aged infants in tropical practice: Frequency, etiology and outcome of hospitalization. J Pediatr Neurosci. 2015 Jan-Mar;10(1):9-12. doi: 10.4103/1817-1745.154315. PMID: 25878734; PMCID: PMC4395963.
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J Pediatr Neurosci. 2015 Jan-Mar;10(1):9-12. doi: 10.4103/1817-1745.154315.

Febrile seizures in one-five aged infants in tropical practice: Frequency, etiology and outcome of hospitalization.

Journal of pediatric neurosciences

Komi Assogba, Bahoura Balaka, Fidato A Touglo, Kossivi M Apetsè, Damelan Kombaté

Affiliations

  1. Neurology Service, Campus University Teaching Hospital, Lomé, Togo.
  2. Department of Pediatric, Sylvanus Olympio University Hospital, Lomé, Togo.

PMID: 25878734 PMCID: PMC4395963 DOI: 10.4103/1817-1745.154315

Abstract

BACKGROUND: Convulsive seizures are the common neurological emergencies in developing regions.

OBJECTIVES: The aim was to determine the prevalence, causes and outcome of seizures in childhood.

PATIENTS AND METHODS: Participants were children aged 1-5 years old, admitted consecutively with a history of febrile convulsions or were presented seizures with fever during hospitalization, in two pediatric university hospitals. The prospective study covered a period from January to December 2013. At admission, emergency care and resuscitation procedures were provided according to the national guidelines. The history included the number and a parental description of seizures. Children with epilepsy, any central nervous system infections and other disease were excluded.

RESULTS: We have recorded 3647 children. Among them, 308 (8.4%) infants had presented with febrile seizures including 174 males and 134 females admitted to both pediatric hospitals (Tokoin University Teaching Hospitals: 206/3070, Campus University Teaching Hospitals: 102/577). Infants from 1 to 3 years age were the most common affected and constituted 65.9% of all patients. The months of September, December and January had recorded the high frequency of admission due to seizures. Regarding the seizures type, generalized tonic-clonic seizures were predominant (46.4%) followed by tonic seizures (17.2%) and status epilepticus in 9%. The etiologies were marked by falciparum malaria (52.3%), and other infections in 47.7%. At discharge, we have noted 11% (34/308) with neurodevelopmental disabilities, 6.7% of epilepsy and 9.7% (30/308) of death.

CONCLUSION: The febrile seizure in child younger 5 years is an indicator of severe malaria in tropical nations. The campaign for "roll back malaria" must continue in developing countries to avoid long-term gross neurological deficits.

Keywords: Childhood; etiologies; febrile seizures; prevalence

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