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Vandana VP, Bindu PS, Sonam K, et al. Speech-Language and swallowing manifestations and rehabilitation in an 11-year-old girl with MELAS syndrome. J Pediatr Neurosci. 2015;10(1):31-4doi: 10.4103/1817-1745.154326.
Vandana, V. P., Bindu, P. S., Sonam, K., Taly, A. B., Gayathri, N., Madhu, N., & Sinha, S. (2015). Speech-Language and swallowing manifestations and rehabilitation in an 11-year-old girl with MELAS syndrome. Journal of pediatric neurosciences, 10(1), 31-4. https://doi.org/10.4103/1817-1745.154326
Vandana, V P, et al. "Speech-Language and swallowing manifestations and rehabilitation in an 11-year-old girl with MELAS syndrome." Journal of pediatric neurosciences vol. 10,1 (2015): 31-4. doi: https://doi.org/10.4103/1817-1745.154326
Vandana VP, Bindu PS, Sonam K, Taly AB, Gayathri N, Madhu N, Sinha S. Speech-Language and swallowing manifestations and rehabilitation in an 11-year-old girl with MELAS syndrome. J Pediatr Neurosci. 2015 Jan-Mar;10(1):31-4. doi: 10.4103/1817-1745.154326. PMID: 25878740; PMCID: PMC4395941.
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J Pediatr Neurosci. 2015 Jan-Mar;10(1):31-4. doi: 10.4103/1817-1745.154326.

Speech-Language and swallowing manifestations and rehabilitation in an 11-year-old girl with MELAS syndrome.

Journal of pediatric neurosciences

V P Vandana, Parayil Sankaran Bindu, Kothari Sonam, Arun B Taly, N Gayathri, N Madhu, S Sinha

Affiliations

  1. Department of Speech Pathology and Audiology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
  2. Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
  3. Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

PMID: 25878740 PMCID: PMC4395941 DOI: 10.4103/1817-1745.154326

Abstract

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare mitochondrial disease. The available studies on MELAS syndrome are limited to evaluation of radiological, audiological, genetic, and neurological findings. Among the various neurological manifestations, speech-language and swallowing manifestations are less discussed in the literature. This report describes the speech-language and swallowing function in an 11-year-old girl with MELAS syndrome. The intervention over a period of 6 months is discussed.

Keywords: 3243A >G mutation; and stroke-like episodes syndrome; encephalopathy; lactic acidosis; mitochondrial DNA; mitochondrial myopathy; rehabilitation; speech-language; swallowing

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