Display options
Share it on

Case Rep Otolaryngol. 2015;2015:404586. doi: 10.1155/2015/404586. Epub 2015 Mar 24.

Laryngeal preservation in managing advanced tracheal adenoid cystic carcinoma.

Case reports in otolaryngology

Thavakumar Subramaniam, Paul Lennon, John Kinsella, James Paul O'Neill

Affiliations

  1. Department of Otolaryngology, Head and Neck Surgery, St James Hospital, Dublin, Ireland.
  2. Department of Otolaryngology, Head and Neck Surgery, Beaumont Hospital, Dublin, Ireland.

PMID: 25878915 PMCID: PMC4387972 DOI: 10.1155/2015/404586

Abstract

A 37-year-old male athlete was diagnosed with primary tracheal adenoid cystic carcinoma following investigation for dyspnea, wheeze, and eventual stridor. Preoperative bronchoscopy revealed a highly vascular tumor 4 cm distal to the cricoid with no gross disease extending to the carina. Imaging revealed circumferential tracheal irregularity immediately inferior to the cricoid, with no definite cricoid invasion. Locoregional extension of disease was noted invading the thyroid and abutment of the carotid approximately 180°. Intraoperative findings identified tracheal mucosal disease extending distal to the carina and proximally at the cricothyroid joints where bilateral functional recurrent nerves were preserved. A decision made to preserve the larynx given the inability to fully resect distal tracheal disease. A 5 cm sleeve resection of the trachea was made with a cricotracheal anastomosis following suprahyoidal muscle release and laryngeal drop-down. The patient was treated with adjuvant radiotherapy including platinum based chemotherapy in an effort to maximise local control. PET scanning three months after therapy revealed no FDG uptake locally or distally.

References

  1. Can Respir J. 2003 Apr;10 (3):143-4 - PubMed
  2. Chest. 2012 May;141(5):1323-6 - PubMed
  3. Isr Med Assoc J. 2006 Aug;8(8):543-7 - PubMed
  4. Int J Clin Oncol. 2006 Oct;11(5):403-6 - PubMed
  5. Natl Cancer Inst Monogr. 1981 Jun;(57):1-1082 - PubMed
  6. Ann Otol Rhinol Laryngol. 1986 Nov-Dec;95(6 Pt 1):582-5 - PubMed
  7. J Clin Oncol. 2007 Dec 1;25(34):5521-3 - PubMed
  8. Cancer Control. 2006 Oct;13(4):286-94 - PubMed
  9. Radiother Oncol. 2013 Nov;109(2):262-8 - PubMed
  10. Ann Surg Oncol. 2007 Feb;14(2):968-76 - PubMed
  11. Int J Radiat Oncol Biol Phys. 2006 Sep 1;66(1):152-9 - PubMed
  12. Am J Clin Oncol. 2006 Apr;29(2):153-7 - PubMed
  13. Eur J Cardiothorac Surg. 2001 Mar;19(3):339-45 - PubMed
  14. J Thorac Cardiovasc Surg. 2005 May;129(5):1006-9 - PubMed
  15. Int J Radiat Oncol Biol Phys. 1995 Jun 15;32(3):619-26 - PubMed
  16. Cancer. 1986 Feb 1;57(3):519-24 - PubMed
  17. Oncology (Williston Park). 1992 Feb;6(2):61-7; discussion 68, 70, 72 - PubMed
  18. Head Neck. 2012 Sep;34(9):1263-8 - PubMed
  19. J Thorac Cardiovasc Surg. 2010 Aug;140(2):387-393.e2 - PubMed
  20. Oncologist. 2013;18(5):579-83 - PubMed

Publication Types