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Gökçe M, Aytaç S, Ünal Ş, et al. Nöroblastomu Taklit Eden t(1;22) Pozitif Akut Megakaryoblastik Lösemili Bir Süt Çocuğu. Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant. Turk J Haematol. 2015;32(1):64-7doi: 10.4274/tjh.2013.0189.
Gökçe, M., Aytaç, S., Ünal, �. �., Altan, �. �., Gümrük, F., & Çetin, M. (2015). Nöroblastomu Taklit Eden t(1;22) Pozitif Akut Megakaryoblastik Lösemili Bir Süt Çocuğu. Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant. Turkish journal of haematology : official journal of Turkish Society of Haematology, 32(1), 64-7. https://doi.org/10.4274/tjh.2013.0189
Gökçe, Müge, et al. "Nöroblastomu Taklit Eden t(1;22) Pozitif Akut Megakaryoblastik Lösemili Bir Süt Çocuğu." Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant. Turkish journal of haematology : official journal of Turkish Society of Haematology vol. 32,1 (2015): 64-7. doi: https://doi.org/10.4274/tjh.2013.0189
Gökçe M, Aytaç S, Ünal Ş, Altan İ, Gümrük F, Çetin M. Nöroblastomu Taklit Eden t(1;22) Pozitif Akut Megakaryoblastik Lösemili Bir Süt Çocuğu. Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant. Turk J Haematol. 2015 Mar 05;32(1):64-7. doi: 10.4274/tjh.2013.0189. PMID: 25805677; PMCID: PMC4439909.
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Turk J Haematol. 2015 Mar 05;32(1):64-7. doi: 10.4274/tjh.2013.0189.

Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Müge Gökçe, Selin Aytaç, Şule Ünal, İlhan Altan, Fatma Gümrük, Mualla Çetin

Affiliations

  1. Hacettepe University Faculty of Medicine, Division of Pediatric Hematology, Ankara, Turkey. E-mail: [email protected].

PMID: 25805677 PMCID: PMC4439909 DOI: 10.4274/tjh.2013.0189

Abstract

Acute megakaryoblastic leukemia (AMKL) with t(1;22) (p13;q13) is an extremely rare subtype of acute myeloid leukemia that is almost always described in infants. t(1;22) (p13;q13)-positive AMKL with extramedullary infiltration has been previously reported only once in the literature. Herein, we report a 3-month-old infant presenting with a pelvic mass and pancytopenia suggesting neuroblastoma. Bone marrow evaluation revealed t(1;22)-positive AMKL that responded well to a regimen containing high-dose cytarabine.

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