Display options
Cite
Aziz F. Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a concise review. Transl Lung Cancer Res. 2012;1(3):208-13doi: 10.3978/j.issn.2218-6751.2012.09.08.
Aziz, F. (2012). Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a concise review. Translational lung cancer research, 1(3), 208-13. https://doi.org/10.3978/j.issn.2218-6751.2012.09.08
Aziz, Fahad. "Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a concise review." Translational lung cancer research vol. 1,3 (2012): 208-13. doi: https://doi.org/10.3978/j.issn.2218-6751.2012.09.08
Aziz F. Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a concise review. Transl Lung Cancer Res. 2012 Sep;1(3):208-13. doi: 10.3978/j.issn.2218-6751.2012.09.08. PMID: 25806182; PMCID: PMC4367563.
Copy Download .nbib Format: NLM
Share it on

Transl Lung Cancer Res. 2012 Sep;1(3):208-13. doi: 10.3978/j.issn.2218-6751.2012.09.08.

Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a concise review.

Translational lung cancer research

Fahad Aziz

Affiliations

  1. Department of Internal Medicine, Section on Hospital Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1021, USA.

PMID: 25806182 PMCID: PMC4367563 DOI: 10.3978/j.issn.2218-6751.2012.09.08

Abstract

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) offers a minimally invasive alternative to mediastinoscopy with additional access to the hilar nodes, a better safety profile, and it removes the costs and hazards of theatre time and general anesthesia with comparable sensitivity, although the negative predictive value of mediastinoscopy (and sample size) is greater. EBUS- TBNA also obtains larger samples than conventional TBNA, has superior performance and theoretically is safer, allowing real-time sampling under direct vision. It can also have predictive value both in sonographic appearance of the nodes and histological characteristics. EBUS-TBNA is therefore indicated for NSCLC staging, diagnosis of lung cancer when there is no endobronchial lesion, and diagnosis of both benign (especially tuberculosis and sarcoidosis) and malignant mediastinal lesions. The procedure is different than for flexible bronchoscopy, takes longer, and requires more training. EBUS-TBNA is more expensive than conventional TBNA but can save costs by reducing the number of more costly mediastinoscopies. In the future, endobronchial ultrasound may have applications in airways disease and pulmonary vascular disease.

Keywords: Endobronchial ultrasound; cancer staging; fine needle aspiration cytology; mediastinum; non-small cell lung carcinoma; sarcoidosis; technique; transbronchial needle aspiration

References

  1. N Engl J Med. 2009 Jul 2;361(1):32-9 - PubMed
  2. Endoscopy. 2006 Jun;38 Suppl 1:S118-22 - PubMed
  3. Respiration. 2009;77(3):298-302 - PubMed
  4. J Thorac Oncol. 2007 Oct;2(10 ):912-5 - PubMed
  5. Thorax. 1992 Jul;47(7):565-7 - PubMed
  6. Semin Thorac Cardiovasc Surg. 2008 Winter;20(4):274-8 - PubMed
  7. Radiol Clin North Am. 1994 May;32(3):521-36 - PubMed
  8. Thorac Surg Clin. 2008 Nov;18(4):349-61 - PubMed
  9. Chest. 1995 Jan;107(1):116-9 - PubMed
  10. Am J Gastroenterol. 2002 Oct;97(10):2559-65 - PubMed
  11. Chest. 2000 Apr;117(4):1186-90 - PubMed
  12. Gastrointest Endosc. 2004 Apr;59(4):475-81 - PubMed
  13. Chest. 2008 Jan;133(1):264-70 - PubMed
  14. Eur Respir J. 2002 Feb;19(2):356-73 - PubMed
  15. Gastroenterol Hepatol. 2007 Jun-Jul;30(6):319-24 - PubMed
  16. Proc Am Thorac Soc. 2009 Apr 15;6(2):180-6 - PubMed
  17. Eur Radiol. 2007 Jul;17 (7):1806-12 - PubMed
  18. Respiration. 2006;73(5):583-6 - PubMed
  19. AJR Am J Roentgenol. 1993 Jan;160(1):175-7 - PubMed
  20. Eur Respir J. 2009 May;33(5):1156-64 - PubMed
  21. Thorax. 2006 Sep;61(9):795-8 - PubMed
  22. J Clin Pathol. 2009 Jan;62(1):57-9 - PubMed
  23. Lung Cancer. 2009 Oct;66(1):80-4 - PubMed
  24. Curr Opin Pulm Med. 2009 Jul;15(4):334-42 - PubMed
  25. Chest. 2003 May;123(5):1693-717 - PubMed
  26. Endoscopy. 2006 Jun;38 Suppl 1:S101-5 - PubMed
  27. Chest. 2007 Sep;132(3 Suppl):178S-201S - PubMed
  28. Am J Gastroenterol. 2003 Jun;98(6):1289-94 - PubMed
  29. Ann Thorac Surg. 1996 May;61(5):1441-5; discussion 1445-6 - PubMed
  30. Curr Opin Pulm Med. 2009 Jul;15(4):308-12 - PubMed
  31. Chest. 2009 Sep;136(3):797-804 - PubMed
  32. Am J Respir Crit Care Med. 1995 Jun;151(6):1998-2002 - PubMed
  33. Am J Clin Pathol. 2008 Sep;130(3):434-43 - PubMed
  34. Thorac Surg Clin. 2008 Nov;18(4):417-21, vii - PubMed
  35. J Clin Oncol. 2005 Nov 20;23 (33):8357-61 - PubMed
  36. Surg Endosc. 2009 Jun;23 (6):1356-9 - PubMed
  37. J Thorac Oncol. 2007 Oct;2(10 ):970-9 - PubMed
  38. Chest. 1997 Jun;111(6):1718-23 - PubMed
  39. Respiration. 2005 Mar-Apr;72(2):182-8 - PubMed

Publication Types