Display options
Cite
Sienkiewicz M, Głowacka A, Poznańska-Kurowska K, et al. The effect of clary sage oil on staphylococci responsible for wound infections. Postepy Dermatol Alergol. 2015;32(1):21-6doi: 10.5114/pdia.2014.40957.
Sienkiewicz, M., Głowacka, A., Poznańska-Kurowska, K., Kaszuba, A., Urbaniak, A., & Kowalczyk, E. (2015). The effect of clary sage oil on staphylococci responsible for wound infections. Postepy dermatologii i alergologii, 32(1), 21-6. https://doi.org/10.5114/pdia.2014.40957
Sienkiewicz, Monika, et al. "The effect of clary sage oil on staphylococci responsible for wound infections." Postepy dermatologii i alergologii vol. 32,1 (2015): 21-6. doi: https://doi.org/10.5114/pdia.2014.40957
Sienkiewicz M, Głowacka A, Poznańska-Kurowska K, Kaszuba A, Urbaniak A, Kowalczyk E. The effect of clary sage oil on staphylococci responsible for wound infections. Postepy Dermatol Alergol. 2015 Feb;32(1):21-6. doi: 10.5114/pdia.2014.40957. Epub 2015 Feb 03. PMID: 25821423; PMCID: PMC4360007.
Copy Download .nbib Format: NLM
Share it on

Postepy Dermatol Alergol. 2015 Feb;32(1):21-6. doi: 10.5114/pdia.2014.40957. Epub 2015 Feb 03.

The effect of clary sage oil on staphylococci responsible for wound infections.

Postepy dermatologii i alergologii

Monika Sienkiewicz, Anna Głowacka, Katarzyna Poznańska-Kurowska, Andrzej Kaszuba, Anna Urbaniak, Edward Kowalczyk

Affiliations

  1. Environmental Biology Department, Basic Sciences Institute, Medical University of Lodz, Lodz, Poland. Head of Department: Anna G?owacka Prof. MUL.
  2. Department of Dermatology, Pediatric Dermatology and Oncology, Medical University of Lodz, Lodz, Poland. Head of Department: Prof. Andrzej Kaszuba MD, PhD.
  3. Pharmacology and Toxicology Department, Medical University of Lodz, Lodz, Poland. Head of Department: Edward Kowalczyk Prof. MUL.

PMID: 25821423 PMCID: PMC4360007 DOI: 10.5114/pdia.2014.40957

Abstract

INTRODUCTION: The spreading of bacterial antibiotic resistance among clinical strains of pathogenic bacteria has made investigators to search for other active antibacterial agents which could provide a valuable complement to the existing therapies.

AIM: To determine the antibacterial activity of clary sage oil (Salvia sclarea L.) against Staphylococcus clinical strains which were isolated from patients with wound infections.

MATERIAL AND METHODS: A comprehensive evaluation of Staphylococcus clinical strain resistance to antibiotics was performed. The constituents of clary sage oil were assayed by GC-FID-MS analysis. The minimal inhibitory concentration (MIC) of the tested essential oil against staphylococci by the micro-dilution broth method was determined.

RESULTS: The clary sage oil was active against Staphylococcus aureus, S. epidermidis and S. xylosus with MIC values ranging from 3.75 to 7.00 µl/ml.

CONCLUSIONS: The results of the in vitro tests encourage to use formulations containing sage oil as the active natural antimicrobial agent. Because of its antimicrobial properties clary sage oil may be applied to treat wounds and skin infections.

Keywords: Staphylococcus; clary sage oil; minimal inhibitory concentration; wounds

References

  1. J Ethnopharmacol. 2011 Mar 8;134(1):89-96 - PubMed
  2. Phytomedicine. 2002 Dec;9(8):721-6 - PubMed
  3. J Ethnopharmacol. 2012 Sep 28;143(2):656-63 - PubMed
  4. Arch Intern Med. 1983 Jan;143(1):32-6 - PubMed
  5. J Int Med Res. 2000 Jul-Aug;28(4):187-90 - PubMed
  6. Curr Opin Infect Dis. 2004 Apr;17(2):91-6 - PubMed
  7. J Am Acad Dermatol. 2004 Jun;50(6):845-9 - PubMed
  8. Fundam Clin Pharmacol. 2005 Feb;19(1):1-16 - PubMed
  9. Burns. 2011 Aug;37(5):808-13 - PubMed
  10. Lancet. 2010 May 1;375(9725):1557-68 - PubMed
  11. Int J Food Microbiol. 2004 Aug 1;94(3):223-53 - PubMed
  12. J Ethnopharmacol. 2010 Aug 9;130(3):593-8 - PubMed
  13. Clin Microbiol Infect. 2001 May;7(5):283-4 - PubMed
  14. Med Chem. 2011 Nov;7(6):674-89 - PubMed
  15. Lipids. 2009 May;44(5):471-6 - PubMed
  16. Phytother Res. 2007 Apr;21(4):308-23 - PubMed
  17. Postgrad Med. 2001 Oct;110(4):63-4, 69-70, 73-6 - PubMed
  18. J Agric Food Chem. 2002 Nov 6;50(23):6688-91 - PubMed
  19. Curr Med Chem. 2003 May;10(10):813-29 - PubMed
  20. Am J Infect Control. 1996 Jun;24(3):186-9 - PubMed

Publication Types