Display options
Cite
Strom KR, Impastato AC, Moy KJ, et al. Gallium(III)-Promoted Halocyclizations of 1,6-Diynes. Org Lett. 2015;17(9):2126-9doi: 10.1021/acs.orglett.5b00716.
Strom, K. R., Impastato, A. C., Moy, K. J., Landreth, A. J., & Snyder, J. K. (2015). Gallium(III)-Promoted Halocyclizations of 1,6-Diynes. Organic letters, 17(9), 2126-9. https://doi.org/10.1021/acs.orglett.5b00716
Strom, Kyle R, et al. "Gallium(III)-Promoted Halocyclizations of 1,6-Diynes." Organic letters vol. 17,9 (2015): 2126-9. doi: https://doi.org/10.1021/acs.orglett.5b00716
Strom KR, Impastato AC, Moy KJ, Landreth AJ, Snyder JK. Gallium(III)-Promoted Halocyclizations of 1,6-Diynes. Org Lett. 2015 May 01;17(9):2126-9. doi: 10.1021/acs.orglett.5b00716. Epub 2015 Apr 17. PMID: 25885017.
Copy Download .nbib Format: NLM
Share it on

Org Lett. 2015 May 01;17(9):2126-9. doi: 10.1021/acs.orglett.5b00716. Epub 2015 Apr 17.

Gallium(III)-Promoted Halocyclizations of 1,6-Diynes.

Organic letters

Kyle R Strom, Anna C Impastato, Kenneth J Moy, Adrian J Landreth, John K Snyder

Affiliations

  1. Department of Chemistry Boston University, Boston, Massachusetts 02215, United States.

PMID: 25885017 DOI: 10.1021/acs.orglett.5b00716

Abstract

Cyclization of 1,6-diynes promoted by stoichiometric Ga(III) halides produces vinyl halides in good to excellent yields. Under acidic conditions, initially formed iodocyclization products undergo in situ Friedel-Crafts cyclizations, giving access to iodoindenopyridines. Application of the vinyl halides in cross-coupling reactions has been explored, and mechanistic aspects of the cyclization are discussed.

Publication Types