J Cardiovasc Thorac Res. 2015;7(1):6-12. doi: 10.15171/jcvtr.2015.02. Epub 2015 Mar 29.
Duration analysis for coronary artery disease patients with chronic chest pain: an output from saudi arabia.
Journal of cardiovascular and thoracic research
Mehwish Hussain, Nazeer Khan, Mudassir Uddin, Mansour M Al-Nozha
Affiliations
Affiliations
- Department of Statistics, University of Karachi, Karachi, Pakistan ; Department of Research, Dow University of Health Sciences, Karachi, Pakistan.
- Department of Research, Jinnah Sindh Medical University, Karachi, Pakistan.
- Department of Statistics, University of Karachi, Karachi, Pakistan.
- Faculty of Medicine, Taibah University, Madinah Munawwarah, Saudi Arabia.
PMID: 25859309
PMCID: PMC4378676 DOI: 10.15171/jcvtr.2015.02
Abstract
INTRODUCTION: Coronary artery disease (CAD) is a persistent public health problem worldwide. Chest pain is one of the perceptible symptoms of the same disease. Literature has found acute chest pain as plausible risk factors for CAD. Nevertheless, none of the study has estimated duration from chronic chest pain to the diagnosis of CAD. The objective of the study was to estimate duration from chronic chest pain to CAD and to assess impact of risk factors on same duration.
METHODS: Data were obtained from community based study on 17,232 Saudi adults. History of patients about onset of chest pain and other risk factors were inquired. Descriptive measures were obtained by Kaplan-Meier curve. Effect of demographic and clinical factors was assessed by Cox regression models.
RESULTS: Out of 24% patients with chest pain, 21% diagnosed with CAD. The average duration was 5 years. About 12% of patients with chest pain diagnosed with CAD after one year. Advancing age, female gender, no exercise and reduced high density lipoprotein (HDL) were significantly hazardous predictors throughout duration from chest pain to diagnosis of CAD.
CONCLUSION: The duration from chest pain to CAD was 5 years. Age, gender, exercise and HDL can be variables of concern to deteriorate hazards of CAD for patients with chest pain.
Keywords: Chronic Chest Pain; Coronary Artery Disease; Diagnosis; Duration Analysis; Predictors
References
- BMC Med. 2010 Jan 21;8:9 - PubMed
- Ann Intern Med. 2004 Jul 6;141(1):57-64 - PubMed
- Am Heart J. 2007 May;153(5):722-31, 731.e1-8 - PubMed
- J Public Health Med. 2000 Sep;22(3):375-85 - PubMed
- Acta Cardiol. 1999 Oct;54(5):257-63 - PubMed
- Eur J Cardiothorac Surg. 2010 May;37(5):1086-92 - PubMed
- Saudi Med J. 2005 May;26(5):824-9 - PubMed
- Saudi Med J. 2004 Sep;25(9):1165-71 - PubMed
- Biostatistics. 2002 Dec;3(4):565-78 - PubMed
- Eur Heart J. 1999 Jun;20(11):796-802 - PubMed
- BMC Med Inform Decis Mak. 2006 Jul 06;6:28 - PubMed
- Swiss Med Wkly. 2008 Jun 14;138(23-24):340-7 - PubMed
- Circulation. 1998 May 12;97(18):1837-47 - PubMed
- Am J Cardiol. 2004 Jul 1;94(1):20-4 - PubMed
- Health Promot Perspect. 2011 Dec 20;1(2):105-10 - PubMed
- Saudi Med J. 2007 Jan;28(1):77-84 - PubMed
- Fam Pract. 2006 Apr;23 (2):167-74 - PubMed
- Saudi Med J. 2004 Nov;25(11):1603-10 - PubMed
- Circulation. 2001 Nov 27;104(22):2746-53 - PubMed
- Saudi Med J. 2008 Feb;29(2):282-7 - PubMed
- J Cardiovasc Thorac Res. 2014;6(1):51-5 - PubMed
- CMAJ. 2010 Sep 7;182(12):1295-300 - PubMed
- CNS Neurol Disord Drug Targets. 2014;13(6):992-1001 - PubMed
- Clin Cardiol. 2014 Mar;37(3):146-51 - PubMed
- Circulation. 2008 Mar 25;117(12):1526-36 - PubMed
- Saudi Med J. 2005 Dec;26(12):1918-25 - PubMed
- J Thorac Cardiovasc Surg. 2009 Oct;138(4):904-10 - PubMed
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