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Couture S, Ouimet MC, Gianoulakis C, et al. Lower Cortisol Activity is Associated with First-Time Driving while Impaired. Subst Abuse. 2015;9:25-32doi: 10.4137/SART.S21353.
Couture, S., Ouimet, M. C., Gianoulakis, C., Tremblay, J., Ng Ying Kin, N., Brochu, S., Pruessner, J., Dedovic, K., & Brown, T. G. (2015). Lower Cortisol Activity is Associated with First-Time Driving while Impaired. Substance abuse : research and treatment, 925-32. https://doi.org/10.4137/SART.S21353
Couture, Sophie, et al. "Lower Cortisol Activity is Associated with First-Time Driving while Impaired." Substance abuse : research and treatment vol. 9 (2015): 25-32. doi: https://doi.org/10.4137/SART.S21353
Couture S, Ouimet MC, Gianoulakis C, Tremblay J, Ng Ying Kin N, Brochu S, Pruessner J, Dedovic K, Brown TG. Lower Cortisol Activity is Associated with First-Time Driving while Impaired. Subst Abuse. 2015 Apr 01;9:25-32. doi: 10.4137/SART.S21353. eCollection 2015. PMID: 25922575; PMCID: PMC4384759.
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Subst Abuse. 2015 Apr 01;9:25-32. doi: 10.4137/SART.S21353. eCollection 2015.

Lower Cortisol Activity is Associated with First-Time Driving while Impaired.

Substance abuse : research and treatment

Sophie Couture, Marie Claude Ouimet, Christina Gianoulakis, Jacques Tremblay, Nmk Ng Ying Kin, Serge Brochu, Jens Pruessner, Katarina Dedovic, Thomas G Brown

Affiliations

  1. Addiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; School of Criminology, Université de Montréal, Montreal, Quebec, Canada. ; Centre jeunesse de Montréal - Institut universitaire, Montreal, Quebec, Canada.
  2. Faculty of Medicine and Health Sciences, Université de Sherbrooke, Longueuil, Quebec, Canada.
  3. Addiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
  4. School of Criminology, Université de Montréal, Montreal, Quebec, Canada.
  5. Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
  6. Addiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; Social and Affective Neuroscience Laboratory, University of California, Los Angeles, Los Angeles, USA.
  7. Addiction Research Program, Douglas Hospital Research Centre, Montreal, Quebec, Canada. ; Department of Psychiatry, McGill University, Montreal, Quebec, Canada. ; Foster Addiction Rehabilitation Centre, St. Philippe de Laprairie, Quebec, Canada.

PMID: 25922575 PMCID: PMC4384759 DOI: 10.4137/SART.S21353

Abstract

Driving while impaired (DWI) is a grave and persistent high-risk behavior. Previous work demonstrated that DWI recidivists had attenuated cortisol reactivity compared to non-DWI drivers. This suggests that cortisol is a neurobiological marker of high-risk driving. The present study tested the hypothesis that this initial finding would extend to first-time DWI (fDWI) offenders compared to non-DWI drivers. Male fDWI offenders (n = 139) and non-DWI drivers (n = 31) were exposed to a stress task, and their salivary cortisol activity (total output and reactivity) was measured. Participants also completed questionnaires on sensation seeking, impulsivity, substance use, and engagement in risky and criminal behaviors. As hypothesized, fDWI offenders, compared to non-DWI drivers, had lower cortisol reactivity; fDWI offenders also showed lower total output. In addition, cortisol activity was the most important predictor of group membership, after accounting for alcohol misuse patterns and consequences and other personality and problem behavior characteristics. The findings indicate that attenuated cortisol activity is an independent factor associated with DWI offending risk at an earlier stage in the DWI trajectory than previously detected.

Keywords: cortisol; impaired driving; neurobiological marker

References

  1. J Abnorm Child Psychol. 2013 Jul;41(5):749-58 - PubMed
  2. Accid Anal Prev. 2008 Jan;40(1):246-53 - PubMed
  3. Accid Anal Prev. 2005 Mar;37(2):341-8 - PubMed
  4. Alcohol Clin Exp Res. 2007 Feb;31(2):185-99 - PubMed
  5. Biol Psychiatry. 1997 May 15;41(10):1045-61 - PubMed
  6. Traffic Inj Prev. 2009 Jun;10(3):220-6 - PubMed
  7. Br J Addict. 1989 Nov;84(11):1353-7 - PubMed
  8. Alcohol Clin Exp Res. 2005 Jul;29(7):1351-5 - PubMed
  9. Psychopharmacology (Berl). 2009 Mar;203(1):1-12 - PubMed
  10. Clin Psychol Rev. 2006 Mar;26(2):179-95 - PubMed
  11. Alcohol Clin Exp Res. 2000 May;24(5):651-8 - PubMed
  12. Alcohol Clin Exp Res. 2003 Mar;27(3):410-23 - PubMed
  13. Addict Behav. 1982;7(4):363-71 - PubMed
  14. Alcohol Clin Exp Res. 2008 Apr;32(4):639-44 - PubMed
  15. Horm Behav. 2001 Nov;40(3):396-402 - PubMed
  16. Accid Anal Prev. 2005 Jul;37(4):619-24 - PubMed
  17. J Am Acad Child Adolesc Psychiatry. 2004 Aug;43(8):1011-8 - PubMed
  18. Psychoneuroendocrinology. 2009 Jan;34(1):2-18 - PubMed
  19. J Subst Abuse Treat. 2001 Dec;21(4):207-15 - PubMed
  20. J Pers. 2010 Oct;78(5):1497-528 - PubMed
  21. J Stud Alcohol Drugs. 2013 Jan;74(1):114-9 - PubMed
  22. Traffic Inj Prev. 2008 Jun;9(2):109-18 - PubMed
  23. Psychoneuroendocrinology. 2008 Jul;33(6):789-98 - PubMed
  24. J Subst Abuse Treat. 2001 Jun;20(4):287-95 - PubMed
  25. Accid Anal Prev. 2008 Sep;40(5):1781-8 - PubMed
  26. Subst Use Misuse. 2005;40(4):427-50 - PubMed
  27. Psychophysiology. 2011 May;48(5):723-32 - PubMed
  28. J Am Acad Child Adolesc Psychiatry. 2000 Nov;39(11):1438-45 - PubMed
  29. J Psychiatr Res. 2007 Oct;41(7):570-8 - PubMed
  30. Psychoneuroendocrinology. 2003 Oct;28(7):916-31 - PubMed
  31. J Crim Justice. 2011 Mar;39(2):137-142 - PubMed
  32. J Subst Abuse Treat. 2007 Mar;32(2):189-98 - PubMed
  33. Drug Alcohol Depend. 1996 Sep;42(1):49-54 - PubMed
  34. J Pers Assess. 2003 Dec;81(3):291-2 - PubMed
  35. Psychoneuroendocrinology. 2004 Jan;29(1):83-98 - PubMed
  36. Alcohol Alcohol. 2003 Mar-Apr;38(2):189-93 - PubMed
  37. Biol Psychol. 2012 Feb;89(2):335-41 - PubMed
  38. Alcohol Alcohol. 2005 Sep-Oct;40(5):474-81 - PubMed
  39. Drug Alcohol Depend. 2004 Nov 11;76(2):135-41 - PubMed
  40. Drug Alcohol Depend. 2002 May 1;66(3):243-53 - PubMed
  41. Biol Psychol. 2008 Apr;78(1):75-86 - PubMed
  42. Addiction. 2012 Feb;107(2):312-22 - PubMed
  43. Am J Addict. 2006 Mar-Apr;15(2):113-24 - PubMed
  44. Alcohol Clin Exp Res. 2000 Nov;24(11):1647-55 - PubMed
  45. JAMA Pediatr. 2014 Jun;168(6):517-22 - PubMed
  46. Drug Alcohol Depend. 2006 Mar 15;82(1):33-40 - PubMed

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