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Schweiger M, Stiasny B, Dave H, et al. Pediatric heart transplantation. J Thorac Dis. 2015;7(3):552-9doi: 10.3978/j.issn.2072-1439.2015.01.38.
Schweiger, M., Stiasny, B., Dave, H., Cavigelli-Brunner, A., Balmer, C., Kretschmar, O., Bürki, C., Klauwer, D., & Hübler, M. (2015). Pediatric heart transplantation. Journal of thoracic disease, 7(3), 552-9. https://doi.org/10.3978/j.issn.2072-1439.2015.01.38
Schweiger, Martin, et al. "Pediatric heart transplantation." Journal of thoracic disease vol. 7,3 (2015): 552-9. doi: https://doi.org/10.3978/j.issn.2072-1439.2015.01.38
Schweiger M, Stiasny B, Dave H, Cavigelli-Brunner A, Balmer C, Kretschmar O, Bürki C, Klauwer D, Hübler M. Pediatric heart transplantation. J Thorac Dis. 2015 Mar;7(3):552-9. doi: 10.3978/j.issn.2072-1439.2015.01.38. PMID: 25922739; PMCID: PMC4387410.
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J Thorac Dis. 2015 Mar;7(3):552-9. doi: 10.3978/j.issn.2072-1439.2015.01.38.

Pediatric heart transplantation.

Journal of thoracic disease

Martin Schweiger, Brian Stiasny, Hitendu Dave, Anna Cavigelli-Brunner, Christian Balmer, Oliver Kretschmar, Christoph Bürki, Dietrich Klauwer, Michael Hübler

Affiliations

  1. 1 Department for Congenital Cardiovascular Surgery, 2 Divisions of Pediatric Cardiology and Children's Research Centre, 3 Department for Anesthesiology, 4 Department of Intensive Care and Neonatology, University Children's Hospital, Zurich, Switzerland.

PMID: 25922739 PMCID: PMC4387410 DOI: 10.3978/j.issn.2072-1439.2015.01.38

Abstract

Pediatric heart transplantation (pHTx) represents a small (14%) but very important and particular part in the field of cardiac transplantation. This treatment has lifelong impact on children. To achieve the best short and especially long-term survival with adequate quality of life, which is of crucial importance for this young patient population, one has to realize and understand the differences with adult HTx. Indication for transplantation, waitlist management including ABO incompatible (ABOi) transplantation and immunosuppression differ. Although young transplant recipients are ultimately likely to be considered for re-transplantation. One has to distinguish between myopathy and complex congenital heart disease (CHD). The differences in anatomy and physiology make the surgical procedure much more complex and create unique challenges. These recipients need a well-organized and educated team with pediatric cardiologists and intensivists, including a high skilled surgeon, which is dedicated to pHTx. Therefore, these types of transplants are best concentrated in specialized centers to achieve promising outcome.

Keywords: Heart transplantation (HTx); heart defects congenital; transplant recipients

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