Display options
Cite
Kallel M, Elloumi F, Khabir A, et al. Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients. Rep Pract Oncol Radiother. 2015;20(3):155-60doi: 10.1016/j.rpor.2015.01.007.
Kallel, M., Elloumi, F., Khabir, A., Ghorbal, L., Chaabouni, S., Amouri, H., Frikha, M., & Daoud, J. (2015). Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients. Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 20(3), 155-60. https://doi.org/10.1016/j.rpor.2015.01.007
Kallel, Mouna, et al. "Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients." Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology vol. 20,3 (2015): 155-60. doi: https://doi.org/10.1016/j.rpor.2015.01.007
Kallel M, Elloumi F, Khabir A, Ghorbal L, Chaabouni S, Amouri H, Frikha M, Daoud J. Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients. Rep Pract Oncol Radiother. 2015 May-Jun;20(3):155-60. doi: 10.1016/j.rpor.2015.01.007. Epub 2015 Mar 06. PMID: 25949218; PMCID: PMC4418592.
Copy Download .nbib Format: NLM
Share it on

Rep Pract Oncol Radiother. 2015 May-Jun;20(3):155-60. doi: 10.1016/j.rpor.2015.01.007. Epub 2015 Mar 06.

Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients.

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Mouna Kallel, Fatma Elloumi, Abdelmajid Khabir, Lilia Ghorbal, Souhir Chaabouni, Habib Amouri, Mounir Frikha, Jamel Daoud

Affiliations

  1. Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia.
  2. Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia ; Cytology and Pathology, Habib Bourguiba University Hospital, Sfax, Tunisia.
  3. Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia ; Gynecology and Obstetric, Hedi Chaker University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia.
  4. Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia ; Medical Oncology, Habib Bourguiba University Hospital, Sfax, Tunisia.

PMID: 25949218 PMCID: PMC4418592 DOI: 10.1016/j.rpor.2015.01.007

Abstract

PURPOSE: To define epidemiological, clinical, therapeutic and prognostic factors influencing survival of breast cancer in young women younger than 35 in southern Tunisia.

MATERIAL AND METHODS: This is a retrospective study of 83 patients younger than 35 years and treated within tumors mammary committee of Sfax.

RESULTS: The mean age was 31.7 years. T2 stage, high grade with positive node tumors were frequent. Breast surgery was performed for 73 patients. Chemotherapy was neo-adjuvant, adjuvant and palliative for respectively 10, 62 and 13 patients. Radiotherapy was delivered for 65 patients with curative intent and for 8 metastatic patients. Endocrine therapy was adjuvant in 38 patients and palliative in 6 cases. The overall survival (OS) at 5 years was 66.8%. Pejorative prognostic factors in uni-variate analysis were clinical T stage (T3, T4), and the number of involved lymph nodes.

CONCLUSION: Despite adequate treatment, the prognosis of breast cancer in young women remains worse. Early diagnosis is necessary to promote outcome.

Keywords: Breast; Cancer; Clinical; Prognosis; Young women

References

  1. Lancet. 2005 Dec 17;366(9503):2087-106 - PubMed
  2. Cancer Radiother. 2003 Jun;7(3):153-9 - PubMed
  3. Oncologist. 2004;9(5):507-17 - PubMed
  4. Cancer Radiother. 2010 Dec;14 (8):698-703 - PubMed
  5. BMJ. 2000 Feb 19;320(7233):474-8 - PubMed
  6. N Engl J Med. 2005 Jun 2;352(22):2302-13 - PubMed
  7. Pathol Biol (Paris). 2003 Sep;51(7):391-2 - PubMed
  8. Ann Oncol. 2013 Sep;24(9):2206-23 - PubMed
  9. Radiother Oncol. 2009 Apr;91(1):23-32 - PubMed
  10. Cancer. 2001 Nov 15;92(10):2523-8 - PubMed
  11. Breast. 2003 Aug;12(4):247-50 - PubMed
  12. Rep Pract Oncol Radiother. 2012 Feb 01;17(2):66-70 - PubMed
  13. Eur J Cancer. 2006 May;42(7):895-904 - PubMed
  14. Bull Cancer. 2008 Feb;95(2):E5-9 - PubMed
  15. Cancer Radiother. 2006 Dec;10 (8):565-71 - PubMed
  16. Bull Cancer. 1999 Mar;86(3):307-13 - PubMed
  17. Radiother Oncol. 2007 Mar;82(3):272-80 - PubMed
  18. Breast Cancer Res. 2010;12(5):212 - PubMed
  19. Int J Radiat Oncol Biol Phys. 2005 Jul 15;62(4):1040-7 - PubMed
  20. N Engl J Med. 2010 Jun 3;362(22):2053-65 - PubMed
  21. Cancer Radiother. 2009 Sep;13(5):434-45 - PubMed
  22. Ann Oncol. 2002 Feb;13(2):273-9 - PubMed
  23. Cancer Epidemiol Biomarkers Prev. 1997 May;6(5):379-83 - PubMed
  24. Rep Pract Oncol Radiother. 2013 May 24;18(4):193-200 - PubMed
  25. Ann Oncol. 2005 Oct;16(10):1569-83 - PubMed
  26. Lancet. 2005 May 14-20;365(9472):1687-717 - PubMed
  27. Int J Radiat Oncol Biol Phys. 2007 Apr 1;67(5):1282-90 - PubMed
  28. J Natl Cancer Inst Monogr. 1994;(16):35-42 - PubMed
  29. J Surg Res. 2003 Jul;113(1):109-13 - PubMed
  30. Eur J Cancer. 2003 May;39(7):932-44 - PubMed
  31. JAMA. 2006 Jun 7;295(21):2492-502 - PubMed
  32. Ann Oncol. 2000 Oct;11(10):1255-62 - PubMed

Publication Types