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Borman N, Graetz K. Spontaneous gall bladder haemorrhage in a renal dialysis patient following haemodialysis with tinzaparin. NDT Plus. 2010;3(4):376-8doi: 10.1093/ndtplus/sfq071.
Borman, N., & Graetz, K. (2010). Spontaneous gall bladder haemorrhage in a renal dialysis patient following haemodialysis with tinzaparin. NDT plus, 3(4), 376-8. https://doi.org/10.1093/ndtplus/sfq071
Borman, Natalie, and Graetz, Keith. "Spontaneous gall bladder haemorrhage in a renal dialysis patient following haemodialysis with tinzaparin." NDT plus vol. 3,4 (2010): 376-8. doi: https://doi.org/10.1093/ndtplus/sfq071
Borman N, Graetz K. Spontaneous gall bladder haemorrhage in a renal dialysis patient following haemodialysis with tinzaparin. NDT Plus. 2010 Aug;3(4):376-8. doi: 10.1093/ndtplus/sfq071. Epub 2010 May 02. PMID: 25949435; PMCID: PMC4421503.
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NDT Plus. 2010 Aug;3(4):376-8. doi: 10.1093/ndtplus/sfq071. Epub 2010 May 02.

Spontaneous gall bladder haemorrhage in a renal dialysis patient following haemodialysis with tinzaparin.

NDT plus

Natalie Borman, Keith Graetz

Affiliations

  1. Department of Nephrology and Renal Transplantation, Wessex Renal and Transplant Unit, Portsmouth , UK.

PMID: 25949435 PMCID: PMC4421503 DOI: 10.1093/ndtplus/sfq071

Abstract

Spontaneous gall bladder haemorrhage is a rare and serious occurrence with a few cases reported in the literature in haemodialysis patients. This report describes this complication following dialysis with a low-molecular-weight heparin (LMWH) tinzaparin. This patient presented with acute right upper quadrant pain and intermittent haematemesis following 4 hours of haemodialysis. Despite being well established on dialysis, LMWH had only been used once previously. There was no history of trauma or pre-existing gall bladder pathology and no clinical or biochemical evidence of inflammation or infection. Computed tomography (CT) scan revealed an extensive gall bladder haemorrhage. The patient was treated conservatively with analgesia, and blood transfusion and symptoms settled without intervention. This case report highlights a rare site of bleeding following LMWH use in a haemodialysis patient.

Keywords: gall bladder haemorrhage; haemodialysis; low-molecular-weight heparin; tinzaparin

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