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Masuda T, Izumi Y, Takeshita H, et al. Granulomatosis with polyangiitis presenting as a choroidal tumor. Case Rep Rheumatol. 2015;2015:271823doi: 10.1155/2015/271823.
Masuda, T., Izumi, Y., Takeshita, H., Kawahara, C., Tsuji, Y., Kurohama, H., Iwanaga, N., Inamoto, M., Kase, K., Ito, M., Kawakami, A., & Migita, K. (2015). Granulomatosis with polyangiitis presenting as a choroidal tumor. Case reports in rheumatology, 2015271823. https://doi.org/10.1155/2015/271823
Masuda, Taro, et al. "Granulomatosis with polyangiitis presenting as a choroidal tumor." Case reports in rheumatology vol. 2015 (2015): 271823. doi: https://doi.org/10.1155/2015/271823
Masuda T, Izumi Y, Takeshita H, Kawahara C, Tsuji Y, Kurohama H, Iwanaga N, Inamoto M, Kase K, Ito M, Kawakami A, Migita K. Granulomatosis with polyangiitis presenting as a choroidal tumor. Case Rep Rheumatol. 2015;2015:271823. doi: 10.1155/2015/271823. Epub 2015 Apr 08. PMID: 25949841; PMCID: PMC4407635.
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Case Rep Rheumatol. 2015;2015:271823. doi: 10.1155/2015/271823. Epub 2015 Apr 08.

Granulomatosis with polyangiitis presenting as a choroidal tumor.

Case reports in rheumatology

Taro Masuda, Yasumori Izumi, Hayato Takeshita, Chieko Kawahara, Yoshika Tsuji, Hirokazu Kurohama, Nozomi Iwanaga, Miwako Inamoto, Keiichi Kase, Masahiro Ito, Atsushi Kawakami, Kiyosi Migita

Affiliations

  1. Departments of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
  2. Department of Pathology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
  3. Department of Ophthalmology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
  4. Department of Otolaryngology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
  5. Department of Rheumatology, Nagasaki University Hospital, Sakamoto 1-7-1, Nagasaki 852-8501, Japan.

PMID: 25949841 PMCID: PMC4407635 DOI: 10.1155/2015/271823

Abstract

Granulomatosis with polyangiitis (GPA) sometimes involves the eye orbit; however, choroidal involvements in GPA had been rarely reported. We report a rare case presenting with a choroidal mass in an 83-year-old Japanese woman who presented with left eye pain. Diagnostic biopsy revealed necrotizing vasculitis with infiltrates of inflammatory cells. Diagnosis was localized granulomatosis with polyangiitis. Combined treatments with corticosteroid plus azathioprine resolved the choroidal mass region. Although treatment with corticosteroid and immunosuppressive agents improves the prognosis of the disease, ocular morbidity is still well recognized. Clinicians should consider a differential diagnosis of GPA in patients with inflammatory choroidal tumors.

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