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Kamran F, Abildgaard OH, Subash AA, et al. Computationally effective solution of the inverse problem in time-of-flight spectroscopy. Opt Express. 2015;23(5):6937-45doi: 10.1364/OE.23.006937.
Kamran, F., Abildgaard, O. H., Subash, A. A., Andersen, P. E., Andersson-Engels, S., & Khoptyar, D. (2015). Computationally effective solution of the inverse problem in time-of-flight spectroscopy. Optics express, 23(5), 6937-45. https://doi.org/10.1364/OE.23.006937
Kamran, Faisal, et al. "Computationally effective solution of the inverse problem in time-of-flight spectroscopy." Optics express vol. 23,5 (2015): 6937-45. doi: https://doi.org/10.1364/OE.23.006937
Kamran F, Abildgaard OH, Subash AA, Andersen PE, Andersson-Engels S, Khoptyar D. Computationally effective solution of the inverse problem in time-of-flight spectroscopy. Opt Express. 2015 Mar 09;23(5):6937-45. doi: 10.1364/OE.23.006937. PMID: 25836913.
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Opt Express. 2015 Mar 09;23(5):6937-45. doi: 10.1364/OE.23.006937.

Computationally effective solution of the inverse problem in time-of-flight spectroscopy.

Optics express

Faisal Kamran, Otto H A Abildgaard, Arman A Subash, Peter E Andersen, Stefan Andersson-Engels, Dmitry Khoptyar

PMID: 25836913 DOI: 10.1364/OE.23.006937

Abstract

Photon time-of-flight (PTOF) spectroscopy enables the estimation of absorption and reduced scattering coefficients of turbid media by measuring the propagation time of short light pulses through turbid medium. The present investigation provides a comparison of the assessed absorption and reduced scattering coefficients from PTOF measurements of intralipid 20% and India ink-based optical phantoms covering a wide range of optical properties relevant for biological tissues and dairy products. Three different models are used to obtain the optical properties by fitting to measured temporal profiles: the Liemert-Kienle model (LKM), the diffusion model (DM) and a white Monte-Carlo (WMC) simulation-based algorithm. For the infinite space geometry, a very good agreement is found between the LKM and WMC, while the results obtained by the DM differ, indicating that the LKM can provide accurate estimation of the optical parameters beyond the limits of the diffusion approximation in a computational effective and accurate manner. This result increases the potential range of applications for PTOF spectroscopy within industrial and biomedical applications.

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