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Morris SK, Demers AM, Lam R, et al. Epidemiology and clinical management of tuberculosis in children in Canada. Paediatr Child Health. 2015;20(2):83-8doi: 10.1093/pch/20.2.83.
Morris, S. K., Demers, A. M., Lam, R., Pell, L. G., Giroux, R. J., & Kitai, I. (2015). Epidemiology and clinical management of tuberculosis in children in Canada. Paediatrics & child health, 20(2), 83-8. https://doi.org/10.1093/pch/20.2.83
Morris, Shaun K, et al. "Epidemiology and clinical management of tuberculosis in children in Canada." Paediatrics & child health vol. 20,2 (2015): 83-8. doi: https://doi.org/10.1093/pch/20.2.83
Morris SK, Demers AM, Lam R, Pell LG, Giroux RJ, Kitai I. Epidemiology and clinical management of tuberculosis in children in Canada. Paediatr Child Health. 2015 Mar;20(2):83-8. doi: 10.1093/pch/20.2.83. PMID: 25838781; PMCID: PMC4373581.
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Paediatr Child Health. 2015 Mar;20(2):83-8. doi: 10.1093/pch/20.2.83.

Epidemiology and clinical management of tuberculosis in children in Canada.

Paediatrics & child health

Shaun K Morris, Anne-Marie Demers, Ray Lam, Lisa G Pell, Ryan Jp Giroux, Ian Kitai

Affiliations

  1. Division of Infectious Diseases, Toronto, Ontario; ; Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario; ; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario;
  2. Department of Microbiology and Immunology and Department of Pediatrics, CHU Sainte-Justine, University of Montreal, Montreal, Quebec;
  3. Division of Infectious Diseases, Toronto, Ontario;
  4. Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario;
  5. Faculty of Medicine, University of Toronto, Toronto, Ontario.
  6. Division of Infectious Diseases, Toronto, Ontario; ; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario;

PMID: 25838781 PMCID: PMC4373581 DOI: 10.1093/pch/20.2.83

Abstract

Although often regarded as a foreign disease, latent tuberculosis or tuberculosis disease will be encountered in many clinical situations by the Canadian child health practitioner. There are key differences between tuberculosis in children and adults. In the present article, the changing epidemiology of tuberculosis in children in Canada and around the world, the pathogenesis of infection, diagnostic tests, and clinical management of childhood latent tuberculosis and tuberculosis disease are reviewed.

Keywords: Children; Diagnosis; Mycobacterium tuberculosis; Pathogenesis; Treatment; Tuberculosis

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