Display options
Cite
Chen YJ, Han Y, Mao M, et al. Interleukin-1β rs1143634 polymorphism and aggressive periodontitis susceptibility: a meta-analysis. Int J Clin Exp Med. 2015;8(2):2308-16
Chen, Y. J., Han, Y., Mao, M., Tan, Y. Q., Leng, W. D., & Zeng, X. T. (2015). Interleukin-1β rs1143634 polymorphism and aggressive periodontitis susceptibility: a meta-analysis. International journal of clinical and experimental medicine, 8(2), 2308-16.
Chen, Yong-Ji, et al. "Interleukin-1β rs1143634 polymorphism and aggressive periodontitis susceptibility: a meta-analysis." International journal of clinical and experimental medicine vol. 8,2 (2015): 2308-16.
Chen YJ, Han Y, Mao M, Tan YQ, Leng WD, Zeng XT. Interleukin-1β rs1143634 polymorphism and aggressive periodontitis susceptibility: a meta-analysis. Int J Clin Exp Med. 2015 Feb 15;8(2):2308-16. eCollection 2015. PMID: 25932167; PMCID: PMC4402814.
Copy Download .nbib Format: NLM
Share it on

Int J Clin Exp Med. 2015 Feb 15;8(2):2308-16. eCollection 2015.

Interleukin-1β rs1143634 polymorphism and aggressive periodontitis susceptibility: a meta-analysis.

International journal of clinical and experimental medicine

Yong-Ji Chen, Ying Han, Min Mao, Ya-Qin Tan, Wei-Dong Leng, Xian-Tao Zeng

Affiliations

  1. Department of Stomatology, Taihe Hospital, Hubei University of Medicine Shiyan 442000, PR China.
  2. Administrative Office, Taihe Hospital, Hubei University of Medicine Shiyan 442000, China.
  3. Department of Stomatology, Taihe Hospital, Hubei University of Medicine Shiyan 442000, PR China ; Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine Shiyan 442000, China ; Center for Evidence-Based and Translational Medicine, Zhongnan Hospital, Wuhan University Wuhan 430071, PR China ; Center for Evidence-Based and Translational Medicine, Wuhan University Wuhan 430071, PR China.

PMID: 25932167 PMCID: PMC4402814

Abstract

Multiple studies had focused on the association between interleukin-1 (IL-1) rs1143634 polymorphism and aggressive periodontitis (AgP) susceptibility, but the results remained inconclusive. Therefore, this meta-analysis was conducted to explore its role in the development of AgP. PubMed and Embase databases were searched up to April 15, 2014. After study selection and data extraction form eligible studies, meta-analysis was performed. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to evaluate the association. All the analysis was performed using Comprehensive Meta-Analysis software. Finally a total of 25 case-control studies were included. The pooled results showed non-association between AgP susceptibility and IL-1 rs1143634 polymorphism [for T vs. C: OR = 0.99, 95% CI = 0.79-1.23; for TT vs. CC: OR = 1.14, 95% CI = 0.78-1.66; for CT vs. CC: OR = 0.97, 95% CI = 0.70-1.36; for (CT + TT) vs. CC: OR = 1.02, 95% CI = 0.76-1.37; for TT vs. (CT + CC): OR = 1.22, 95% CI = 0.85-1.75]. Subgroup analyses remain did not find any association. No publication bias was detected. Hence, our meta-analysis showed that IL-1β rs1143634 polymorphism is not linked to AgP susceptibility, regardless of ethnicity.

Keywords: Interleukin-1; aggressive periodontitis; meta-analysis; periodontitis; polymorphism

References

  1. Mol Biol Rep. 2012 Oct;39(10):9319-29 - PubMed
  2. Braz Oral Res. 2012;26 Suppl 1:25-31 - PubMed
  3. J Transl Med. 2005 Sep 30;3:37 - PubMed
  4. Hum Immunol. 2011 Oct;72(10):940-6 - PubMed
  5. J Exp Med. 1984 Aug 1;160(2):618-23 - PubMed
  6. Genes Immun. 2005 Feb;6(1):44-52 - PubMed
  7. Lancet. 2005 Nov 19;366(9499):1809-20 - PubMed
  8. PLoS One. 2013 May 21;8(5):e63654 - PubMed
  9. Diabetologia. 2012 Jan;55(1):21-31 - PubMed
  10. J Indian Soc Periodontol. 2009 May;13(2):109-13 - PubMed
  11. DNA Cell Biol. 2013 Jul;32(7):409-13 - PubMed
  12. J Periodontol. 2014 Nov;85(11):e354-62 - PubMed
  13. Periodontol 2000. 2004;35:158-82 - PubMed
  14. J Clin Periodontol. 2001 May;28(5):430-6 - PubMed
  15. Periodontol 2000. 2007;43:102-32 - PubMed
  16. Mol Biol Rep. 2014 Oct;41(10):6713-7 - PubMed
  17. Indian J Dermatol Venereol Leprol. 2012 May-Jun;78(3):242-50 - PubMed
  18. Hua Xi Kou Qiang Yi Xue Za Zhi. 2002 Feb;20(1):48-51 - PubMed
  19. J Clin Periodontol. 2010 Mar;37(3):255-65 - PubMed
  20. PLoS One. 2013;8(3):e59513 - PubMed
  21. J Periodontol. 2003 Dec;74(12):1796-802 - PubMed
  22. BMJ. 2009 Jul 21;339:b2535 - PubMed
  23. J Dent Res. 2000 Oct;79(10):1758-64 - PubMed
  24. Genet Couns. 2013;24(1):21-35 - PubMed
  25. J Clin Periodontol. 1991 Aug;18(7):548-54 - PubMed
  26. J Oral Sci. 2008 Jun;50(2):151-9 - PubMed
  27. J Dent Res. 2005 Dec;84(12):1149-53 - PubMed
  28. ISRN Dent. 2011;2011:682564 - PubMed
  29. J Clin Periodontol. 2000 Sep;27(9):682-9 - PubMed
  30. Indian J Dent Res. 2010 Oct-Dec;21(4):568-74 - PubMed
  31. Psychol Methods. 2006 Jun;11(2):193-206 - PubMed
  32. Arch Oral Biol. 2011 Mar;56(3):269-76 - PubMed
  33. J Periodontol. 2012 Sep;83(9):1095-103 - PubMed
  34. PLoS One. 2012;7(10):e46508 - PubMed
  35. Eur J Oral Sci. 2003 Oct;111(5):395-9 - PubMed
  36. Periodontol 2000. 2004;35:21-41 - PubMed
  37. J Clin Periodontol. 2006 Nov;33(11):765-70 - PubMed
  38. PLoS One. 2013 Oct 23;8(10):e79017 - PubMed
  39. Periodontol 2000. 2002;29:7-10 - PubMed
  40. J Evid Based Med. 2015 Feb;8(1):2-10 - PubMed
  41. J Periodontol. 2000 May;71(5):723-8 - PubMed
  42. J Clin Periodontol. 1998 Oct;25(10):781-5 - PubMed
  43. Contemp Clin Dent. 2012 Apr;3(2):144-9 - PubMed
  44. Mol Biol Rep. 2013 Oct;40(10):5987-92 - PubMed
  45. J Clin Periodontol. 2002 Oct;29(10):882-8 - PubMed
  46. Genomics. 2008 Nov;92(5):309-15 - PubMed
  47. Cytokine Growth Factor Rev. 2002 Dec;13(6):483-502 - PubMed
  48. Iran J Allergy Asthma Immunol. 2013 Aug 28;12(4):345-51 - PubMed
  49. J Dent Res. 2010 May;89(5):457-61 - PubMed
  50. J Dent Res. 2013 Dec;92(12):1081-8 - PubMed
  51. J Periodontol. 2004 Dec;75(12):1627-35 - PubMed
  52. BMC Cancer. 2014 Jun 26;14:469 - PubMed
  53. BMJ. 1997 Sep 13;315(7109):629-34 - PubMed
  54. J Periodontal Res. 2005 Aug;40(4):306-11 - PubMed
  55. J Periodontol. 2007 Mar;78(3):475-92 - PubMed
  56. Int J Dent Hyg. 2006 Sep;4 Suppl 1:34-8; discussion 50-2 - PubMed
  57. J Oral Pathol Med. 1996 May;25(5):225-31 - PubMed
  58. J Periodontal Res. 2002 Feb;37(1):37-41 - PubMed
  59. Gene. 2013 Dec 10;532(1):114-9 - PubMed
  60. Hum Immunol. 2013 Mar;74(3):371-8 - PubMed
  61. J Periodontol. 2004 Nov;75(11):1509-15 - PubMed

Publication Types