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Simon D, Mascarenhas R, Saltzman BM, et al. The Relationship between Anterior Cruciate Ligament Injury and Osteoarthritis of the Knee. Adv Orthop. 2015;2015:928301doi: 10.1155/2015/928301.
Simon, D., Mascarenhas, R., Saltzman, B. M., Rollins, M., Bach, B. R., & MacDonald, P. (2015). The Relationship between Anterior Cruciate Ligament Injury and Osteoarthritis of the Knee. Advances in orthopedics, 2015928301. https://doi.org/10.1155/2015/928301
Simon, David, et al. "The Relationship between Anterior Cruciate Ligament Injury and Osteoarthritis of the Knee." Advances in orthopedics vol. 2015 (2015): 928301. doi: https://doi.org/10.1155/2015/928301
Simon D, Mascarenhas R, Saltzman BM, Rollins M, Bach BR, MacDonald P. The Relationship between Anterior Cruciate Ligament Injury and Osteoarthritis of the Knee. Adv Orthop. 2015;2015:928301. doi: 10.1155/2015/928301. Epub 2015 Apr 19. PMID: 25954533; PMCID: PMC4410751.
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Adv Orthop. 2015;2015:928301. doi: 10.1155/2015/928301. Epub 2015 Apr 19.

The Relationship between Anterior Cruciate Ligament Injury and Osteoarthritis of the Knee.

Advances in orthopedics

David Simon, Randy Mascarenhas, Bryan M Saltzman, Meaghan Rollins, Bernard R Bach, Peter MacDonald

Affiliations

  1. Pan Am Clinic, Section of Orthopaedic Surgery, University of Manitoba, 75 Poseidon Bay, Winnipeg, MB, Canada R3M 3E4.
  2. Section of Orthopaedic Surgery, Rush University Medical Center, 1611 West Harrison Street, Suite 300, Chicago, IL 60612, USA.

PMID: 25954533 PMCID: PMC4410751 DOI: 10.1155/2015/928301

Abstract

Anterior cruciate ligament (ACL) tears are a common injury, particularly in the athletic and youth populations. The known association between ACL injury and subsequent osteoarthritis (OA) of the knee merits a more in-depth understanding of the relationship between the ACL-injured knee and osteoarthritis. ACL injury, especially with concomitant meniscal or other ligamentous pathology, predisposes the knee to an increased risk of osteoarthritis. ACL insufficiency results in deterioration of the normal physiologic knee bending culminating in increased anterior tibial translation and increased internal tibial rotation. This leads to increased mean contact stresses in the posterior medial and lateral compartments under anterior and rotational loading. However, surgical reconstruction of the ACL has not been shown to reduce the risk of future OA development back to baseline and has variability based on operative factors of graft choice, timing of surgery, presence of meniscal and chondral abnormalities, and surgical technique. Known strategies to prevent OA development are applicable to patients with ACL deficiency or after ACL reconstruction and include weight management, avoidance of excessive musculoskeletal loading, and strength training. Reconstruction of the ACL does not necessarily prevent osteoarthritis in many of these patients and may depend on several external variables.

References

  1. Knee Surg Sports Traumatol Arthrosc. 1999;7(3):160-5 - PubMed
  2. Am J Sports Med. 2011 Dec;39(12 ):2595-603 - PubMed
  3. Osteoarthritis Cartilage. 2014 Jan;22(1):84-90 - PubMed
  4. Acta Radiol. 1988 Sep-Oct;29(5):559-63 - PubMed
  5. Am J Sports Med. 2008 Sep;36(9):1717-25 - PubMed
  6. Arthroscopy. 2013 May;29(5):898-905 - PubMed
  7. Osteoarthritis Cartilage. 2010 Jun;18(6):769-75 - PubMed
  8. Curr Opin Rheumatol. 2005 Mar;17 (2):195-200 - PubMed
  9. Ann Intern Med. 2000 Sep 5;133(5):321-8 - PubMed
  10. Knee. 2013 Oct;20(5):346-53 - PubMed
  11. Am J Sports Med. 2014 May;42(5):1247-55 - PubMed
  12. Knee Surg Sports Traumatol Arthrosc. 2011 Mar;19(3):462-72 - PubMed
  13. Arthroscopy. 2010 Oct;26(10 ):1296-301 - PubMed
  14. J Athl Train. 2015 Jan;50(1):110-2 - PubMed
  15. Eur J Orthop Surg Traumatol. 2014 May;24(4):559-65 - PubMed
  16. J Bone Joint Surg Am. 2014 Feb 19;96(4):292-300 - PubMed
  17. Br J Sports Med. 2013 Jan;47(2):66-70 - PubMed
  18. Biomaterials. 2014 Sep;35(28):8154-63 - PubMed
  19. J Orthop Res. 2006 May;24(5):1052-61 - PubMed
  20. Radiology. 2012 Aug;264(2):531-41 - PubMed
  21. Knee Surg Sports Traumatol Arthrosc. 2013 Sep;21(9):2040-7 - PubMed
  22. Am J Sports Med. 2009 Jul;37(7):1434-43 - PubMed
  23. Am J Sports Med. 2014 May;42(5):1049-57 - PubMed
  24. Br J Sports Med. 2011 Apr;45(4):304-9 - PubMed
  25. Osteoarthritis Cartilage. 1995 Dec;3(4):261-7 - PubMed
  26. Unfallchirurg. 2003 May;106(5):374-9 - PubMed
  27. Am J Sports Med. 2010 Mar;38(3):455-63 - PubMed
  28. Int Orthop. 1991;15(4):367-71 - PubMed
  29. Clin Biomech (Bristol, Avon). 2010 Mar;25(3):222-9 - PubMed
  30. Knee. 2009 Aug;16(4):239-44 - PubMed
  31. Knee. 2005 Jan;12 (1):33-5 - PubMed
  32. J Biomech. 2014 Jul 18;47(10 ):2526-30 - PubMed
  33. Am J Sports Med. 1993 Sep-Oct;21(5):672-9 - PubMed
  34. Am J Sports Med. 2012 Mar;40(3):595-605 - PubMed
  35. Gait Posture. 2012 Mar;35(3):467-71 - PubMed
  36. Am J Sports Med. 2013 Nov;41(11):2484-91 - PubMed
  37. Arthroscopy. 2012 Nov;28(11):1702-9 - PubMed
  38. Am J Sports Med. 2013 Oct;41(10):2340-6 - PubMed
  39. Med Sci Sports Exerc. 2005 Jan;37(1):124-9 - PubMed
  40. Sports Med. 2003;33(14 ):1075-89 - PubMed
  41. Arthroscopy. 2011 Jan;27(1):65-76 - PubMed
  42. Scand J Med Sci Sports. 2000 Apr;10 (2):78-84 - PubMed
  43. Injury. 2003 May;34(5):343-5 - PubMed
  44. Magn Reson Imaging. 2014 Dec;32(10 ):1290-6 - PubMed
  45. Am J Sports Med. 2014 Jul;42(7):1583-91 - PubMed
  46. Osteoarthritis Cartilage. 2015 Jan;23 (1):1-12 - PubMed
  47. Am J Sports Med. 2012 Feb;40(2):276-85 - PubMed
  48. Knee Surg Sports Traumatol Arthrosc. 2014 May;22(5):1061-9 - PubMed
  49. J Strength Cond Res. 2014 Feb;28(2):390-400 - PubMed
  50. Clin Orthop Relat Res. 2013 Nov;471(11):3504-11 - PubMed
  51. J Inflamm (Lond). 2014 Nov 01;11(1):34 - PubMed
  52. Ann Rheum Dis. 2004 Mar;63(3):269-73 - PubMed
  53. Clin Orthop Relat Res. 1999 Jan;(358):188-93 - PubMed
  54. Knee Surg Sports Traumatol Arthrosc. 2006 Nov;14 (11):1060-9 - PubMed
  55. Osteoarthritis Cartilage. 2015 Apr;23 (4):581-8 - PubMed
  56. Clin Orthop Relat Res. 1983 Jan-Feb;(172):158-63 - PubMed
  57. Exp Gerontol. 2014 Jul;55:44-8 - PubMed
  58. Knee Surg Sports Traumatol Arthrosc. 2008 May;16(5):442-8 - PubMed
  59. Am J Sports Med. 2007 Apr;35(4):564-74 - PubMed
  60. Am J Sports Med. 2014 Sep;42(9):2242-52 - PubMed
  61. Am J Sports Med. 1994 Sep-Oct;22(5):632-44 - PubMed
  62. Bone Joint Res. 2014 Feb 04;3(2):20-31 - PubMed
  63. J Bone Joint Surg Am. 2014 Jan 1;96(1):2-10 - PubMed
  64. Am J Sports Med. 2013 Aug;41(8):1762-70 - PubMed
  65. Bone Joint J. 2013 Nov;95-B(11):1562-9 - PubMed
  66. J Bone Joint Surg Am. 1981 Jul;63(6):954-60 - PubMed
  67. J Bone Joint Surg Am. 1980 Mar;62(2):259-70 - PubMed
  68. Sports Health. 2012 Mar;4(2):155-61 - PubMed
  69. Osteoarthritis Cartilage. 2013 Aug;21(8):1058-67 - PubMed
  70. Knee Surg Sports Traumatol Arthrosc. 2009 Jan;17 (1):30-4 - PubMed
  71. Am J Phys Med Rehabil. 2010 Jul;89(7):541-8 - PubMed
  72. Am J Sports Med. 2010 Jan;38(1):25-34 - PubMed
  73. Br J Sports Med. 2009 May;43(5):347-51 - PubMed
  74. Am J Sports Med. 2013 Sep;41(9):2108-16 - PubMed
  75. Open Orthop J. 2013 Aug 19;7:292-300 - PubMed
  76. Am J Sports Med. 2012 Jul;40(7):1511-8 - PubMed
  77. Nat Rev Rheumatol. 2011 Jan;7(1):57-63 - PubMed
  78. Am J Sports Med. 2008 Apr;36(4):656-62 - PubMed
  79. Chin Med J (Engl). 2010 Nov;123(21):3137-42 - PubMed
  80. Orthop Traumatol Surg Res. 2014 Feb;100(1):49-58 - PubMed
  81. Med Sci Sports Exerc. 2012 Aug;44(8):1490-6 - PubMed
  82. Int Orthop. 2011 Jul;35(7):1093-7 - PubMed
  83. Knee Surg Sports Traumatol Arthrosc. 2013 Apr;21(4):942-9 - PubMed
  84. J Sports Sci Med. 2013 Sep 01;12(3):579-87 - PubMed
  85. Am J Sports Med. 2014 Nov;42(11):2769-76 - PubMed
  86. J Orthop Res. 2013 Feb;31(2):315-21 - PubMed
  87. Am J Sports Med. 2003 Jan-Feb;31(1):2-11 - PubMed
  88. J Sci Med Sport. 2009 Jul;12 (4):445-8 - PubMed
  89. Clin Orthop Relat Res. 1985 Sep;(198):77-80 - PubMed
  90. Hum Mov Sci. 2012 Feb;31(1):222-35 - PubMed
  91. Arthroscopy. 1986;2(2):98-102 - PubMed
  92. Br Med Bull. 2011;99:89-106 - PubMed
  93. Strategies Trauma Limb Reconstr. 2007 Apr;2(1):1-12 - PubMed
  94. Clin Orthop Relat Res. 1998 Nov;(356):208-12 - PubMed
  95. J Bone Joint Surg Am. 1982 Feb;64(2):258-64 - PubMed
  96. J Bone Joint Surg Am. 1984 Feb;66(2):242-52 - PubMed
  97. Am J Sports Med. 2008 Oct;36(10 ):2028-36 - PubMed
  98. Skeletal Radiol. 2014 Feb;43(2):247-50 - PubMed
  99. Am J Sports Med. 2013 Apr;41(4):815-25 - PubMed
  100. Am J Sports Med. 2012 Feb;40(2):404-13 - PubMed
  101. Am J Sports Med. 2014 Feb;42(2):302-11 - PubMed
  102. Am J Sports Med. 2007 Oct;35(10 ):1756-69 - PubMed
  103. J Bone Joint Surg Br. 2005 Dec;87(12 ):1639-42 - PubMed

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