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Case Reports Hepatol. 2011;2011:314231. doi: 10.1155/2011/314231. Epub 2012 Jan 11.

A case of prolonged cholestatic hepatitis induced by azithromycin in a young woman.

Case reports in hepatology

Caterina Maggioli, Luca Santi, Giacomo Zaccherini, Vittoria Bevilacqua, Francesca Giunchi, Paolo Caraceni

Affiliations

  1. Department of Clinical Medicine, Alma Mater Studiorum University of Bologna, Policlinico Sant'Orsola, Via Albertoni 15, 40138 Bologna, Italy.
  2. Department of Internal Medicine, Geriatric and Renal Diseases, Alma Mater Studiorum University of Bologna, Policlinico Sant'Orsola, Via Albertoni 15, 40138 Bologna, Italy.

PMID: 25954540 PMCID: PMC4411890 DOI: 10.1155/2011/314231

Abstract

Azithromycin, a semisynthetic macrolides, is frequently prescribed for the treatment of middle ear and upper respiratory tract infections, bronchitis, and community-acquired pneumonia. This antibiotic is usually well tolerated, and a rapid resolving cholestatic hepatitis has been described up to now only in six patients all, except one, over 65 years of age. We here report the case of a prolonged cholestatic hepatitis after administration of azithromycin in a young woman with no history of liver disease.

References

  1. Med J Aust. 1993 May 3;158(9):600-2 - PubMed
  2. Infect Dis Clin North Am. 2009 Dec;23 (4):997-1026, ix-x - PubMed
  3. Drug Saf. 1999 Jan;20(1):25-41 - PubMed
  4. Semin Liver Dis. 2002;22(2):157-67 - PubMed
  5. Clin Pharmacokinet. 1993 Nov;25(5):370-4 - PubMed
  6. Am J Health Syst Pharm. 2010 May 15;67(10 ):810-4 - PubMed
  7. J Pediatr Gastroenterol Nutr. 2011 Aug;53(2):182-9 - PubMed
  8. J Gen Intern Med. 1992 Mar-Apr;7(2):199-209 - PubMed
  9. Semin Liver Dis. 2002;22(2):207-10 - PubMed
  10. Am J Med. 1984 May;76(5):931-4 - PubMed
  11. Dig Dis Sci. 2002 Oct;47(10):2186-8 - PubMed
  12. Am J Med. 2005 Dec;118(12):1438-9 - PubMed
  13. Drug Saf. 1996 Jul;15(1):79-85 - PubMed
  14. Hepatology. 1997 Sep;26(3):664-9 - PubMed

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