Display options
Cite
Khan M, Wasim A, Mirrakhimov AE, et al. Case report of a patient with left ventricular assistance device undergoing chemotherapy for a new diagnosis of lung cancer. Case Rep Oncol Med. 2015;2015:163727doi: 10.1155/2015/163727.
Khan, M., Wasim, A., Mirrakhimov, A. E., McMahon, B. A., Judge, D. P., Chu, L. C., Banavali, A., & Zeidan, A. M. (2015). Case report of a patient with left ventricular assistance device undergoing chemotherapy for a new diagnosis of lung cancer. Case reports in oncological medicine, 2015163727. https://doi.org/10.1155/2015/163727
Khan, Maliha, et al. "Case report of a patient with left ventricular assistance device undergoing chemotherapy for a new diagnosis of lung cancer." Case reports in oncological medicine vol. 2015 (2015): 163727. doi: https://doi.org/10.1155/2015/163727
Khan M, Wasim A, Mirrakhimov AE, McMahon BA, Judge DP, Chu LC, Banavali A, Zeidan AM. Case report of a patient with left ventricular assistance device undergoing chemotherapy for a new diagnosis of lung cancer. Case Rep Oncol Med. 2015;2015:163727. doi: 10.1155/2015/163727. Epub 2015 Mar 22. PMID: 25874142; PMCID: PMC4385621.
Copy Download .nbib Format: NLM
Share it on

Case Rep Oncol Med. 2015;2015:163727. doi: 10.1155/2015/163727. Epub 2015 Mar 22.

Case report of a patient with left ventricular assistance device undergoing chemotherapy for a new diagnosis of lung cancer.

Case reports in oncological medicine

Maliha Khan, Anum Wasim, Aibek E Mirrakhimov, Blaithin A McMahon, Daniel P Judge, Linda C Chu, Ashtami Banavali, Amer M Zeidan

Affiliations

  1. Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA.
  2. Dow University of Health Sciences, Karachi, Sindh 74200, Pakistan.
  3. Johns Hopkins University, Baltimore, MD 21287, USA.
  4. Yale University, New Haven, CT 06510, USA.

PMID: 25874142 PMCID: PMC4385621 DOI: 10.1155/2015/163727

Abstract

The optimal management of cancer in patients with severe heart failure is not defined. This issue is particularly challenging when a diagnosis of limited-stage small cell lung cancer (SCLC) is made incidentally in the context of evaluating patient for candidacy for cardiac transplantation. Limited-stage SCLC is typically managed on a curative therapeutic paradigm with combined modality approach involving chemotherapy and radiation. Even with excellent performance status and good organ function, the presence of severe cardiomyopathy poses significant challenges to the delivery of even single modality approach with chemotherapy or radiotherapy, let alone the typical curative combined modality approach. With mechanical left ventricular devices to provide cardiac support, treatment options for cancer in the setting of advanced heart failure may be improved. Here we discuss the therapeutic dilemma involving a patient with severe cardiomyopathy and left ventricular assistant device (LVAD) who was found to have limited-stage SCLC during the evaluation process for cardiac transplantation.

References

  1. J Clin Oncol. 2012 Jun 20;30(18):e163-4 - PubMed
  2. Interact Cardiovasc Thorac Surg. 2011 Dec;13(6):676-8 - PubMed
  3. N Engl J Med. 2009 Dec 3;361(23):2241-51 - PubMed
  4. Transplantation. 1991 Jul;52(1):82-5 - PubMed
  5. Ann Thorac Surg. 2009 Jun;87(6):1934-6 - PubMed
  6. Case Rep Transplant. 2012;2012:716201 - PubMed
  7. J Natl Compr Canc Netw. 2013 Jan 1;11(1):78-98 - PubMed
  8. J Clin Oncol. 2012 May 10;30(14):1692-8 - PubMed
  9. J Clin Oncol. 1999 Jan;17(1):409-22 - PubMed
  10. Circulation. 1995 Dec 15;92(12):3593-612 - PubMed
  11. Heart. 2002 Feb;87(2):177-84 - PubMed
  12. J Clin Oncol. 1992 Jun;10(6):890-5 - PubMed

Publication Types