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Brzozowa M, Wyrobiec G, Kołodziej I, et al. The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract. Prz Gastroenterol. 2015;10(1):7-11doi: 10.5114/pg.2014.47502.
Brzozowa, M., Wyrobiec, G., Kołodziej, I., Sitarski, M., Matysiak, N., Reichman-Warmusz, E., Żaba, M., & Wojnicz, R. (2015). The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract. Przeglad gastroenterologiczny, 10(1), 7-11. https://doi.org/10.5114/pg.2014.47502
Brzozowa, Marlena, et al. "The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract." Przeglad gastroenterologiczny vol. 10,1 (2015): 7-11. doi: https://doi.org/10.5114/pg.2014.47502
Brzozowa M, Wyrobiec G, Kołodziej I, Sitarski M, Matysiak N, Reichman-Warmusz E, Żaba M, Wojnicz R. The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract. Prz Gastroenterol. 2015;10(1):7-11. doi: 10.5114/pg.2014.47502. Epub 2015 Jan 14. PMID: 25960808; PMCID: PMC4411408.
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Prz Gastroenterol. 2015;10(1):7-11. doi: 10.5114/pg.2014.47502. Epub 2015 Jan 14.

The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract.

Przeglad gastroenterologiczny

Marlena Brzozowa, Grzegorz Wyrobiec, Izabela Kołodziej, Mateusz Sitarski, Natalia Matysiak, Edyta Reichman-Warmusz, Małgorzata Żaba, Romuald Wojnicz

Affiliations

  1. Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.

PMID: 25960808 PMCID: PMC4411408 DOI: 10.5114/pg.2014.47502

Abstract

Vimentin is an intermediate filament protein normally expressed in cells of mesenchymal origin, e.g. myofibroblasts, chondrocytes, macrophages, and endothelial cells. The expression of vimentin, which has been thought of as the main mesenchymal marker, is also detected in tumour tissue. In tumours of the gastrointestinal tract vimentin expression is usually correlated with advanced stage of tumour, lymph node metastasis, and patient survival.

Keywords: E-cadherin; gastrointestinal tumours; vimentin

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