Display options
Cite
Cohen A, Combes V, Grau GE. MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood. J Neuroinfect Dis. 2015;6(1)
Cohen, A., Combes, V., & Grau, G. E. (2015). MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood. Journal of neuroinfectious diseases, 6(1), .
Cohen, Amy, et al. "MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood." Journal of neuroinfectious diseases vol. 6,1 (2015).
Cohen A, Combes V, Grau GE. MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood. J Neuroinfect Dis. 2015 Mar;6(1). PMID: 26005686; PMCID: PMC4441219.
Copy Download .nbib Format: NLM
Share it on

J Neuroinfect Dis. 2015 Mar;6(1).

MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood.

Journal of neuroinfectious diseases

Amy Cohen, Valéry Combes, Georges Er Grau

Affiliations

  1. Vascular Immunology Unit, Discipline of Pathology, School of Medical Sciences & Marie Bashir Institute, The University of Sydney, Australia.

PMID: 26005686 PMCID: PMC4441219

Abstract

Malaria is a mosquito-borne infectious disease caused by parasitic protozoa of the genus Plasmodium. It remains a major problem affecting humans today, especially children. However, the pathogenesis of malaria, especially severe malaria, remains incompletely understood, hindering our ability to treat this disease. Of recent interest is the role that small, non-coding RNAs play in the progression, pathogenesis of, and resistance to, malaria. Independent studies have now revealed the presence of microRNA (miRNA) in the malaria parasite, vector, and host, though these studies are relatively few. Here, we review these studies, focusing on the roles specific miRNA have in the disease, and how they may be harnessed for therapeutic purposes.

Keywords: Immunopathology; Inflammation; Malaria; Protective immunity; microRNA

References

  1. Nat Rev Immunol. 2005 Sep;5(9):722-35 - PubMed
  2. Parasite Immunol. 2003 Mar;25(3):113-8 - PubMed
  3. Malar J. 2008 Mar 10;7:47 - PubMed
  4. Cell Host Microbe. 2012 Aug 16;12(2):187-99 - PubMed
  5. FEBS Lett. 2006 Oct 2;580(22):5185-8 - PubMed
  6. Lancet. 2002 Apr 13;359(9314):1311-2 - PubMed
  7. Prog Neurobiol. 2010 Jun;91(2):140-51 - PubMed
  8. BMC Med Genomics. 2008 Aug 13;1:37 - PubMed
  9. RNA Biol. 2012 Jun;9(6):742-50 - PubMed
  10. Nature. 2001 Aug 30;412(6850):875-6 - PubMed
  11. Trends Immunol. 2010 Jul;31(7):260-9 - PubMed
  12. Mol Ther. 2014 Dec;22(12):2130-41 - PubMed
  13. Annu Rev Cell Dev Biol. 2007;23:175-205 - PubMed
  14. Cell Cycle. 2008 Nov 15;7(22):3564-76 - PubMed
  15. BMC Genomics. 2008 May 23;9:244 - PubMed
  16. Parasitol Res. 2011 May;108(5):1111-21 - PubMed
  17. Hepatology. 2010 Mar;51(3):1055-61 - PubMed
  18. BMC Genomics. 2012 Aug 02;13:366 - PubMed
  19. Int J Parasitol. 2006 May 1;36(5):541-6 - PubMed
  20. Nucleic Acids Res. 2009 Jun;37(11):3788-98 - PubMed
  21. World J Gastroenterol. 2009 Apr 14;15(14):1665-72 - PubMed
  22. Blood. 1989 Sep;74(4):1213-21 - PubMed
  23. Annu Rev Immunol. 2012;30:295-312 - PubMed
  24. Steroids. 2010 Dec;75(12):998-1004 - PubMed
  25. J Immunol. 2011 Dec 1;187(11):5834-41 - PubMed
  26. J Biol Chem. 2010 Jan 1;285(1):216-25 - PubMed
  27. PLoS One. 2011 Mar 08;6(3):e16956 - PubMed
  28. Science. 2005 Jan 7;307(5706):82-6 - PubMed
  29. Parasitol Today. 1994 Oct;10(10):412-4 - PubMed
  30. Trends Parasitol. 2011 Nov;27(11):481-6 - PubMed
  31. PLoS One. 2014 May 27;9(5):e98402 - PubMed
  32. Annu Rev Immunol. 2009;27:147-63 - PubMed
  33. Br J Cancer. 2010 Aug 10;103(4):532-41 - PubMed
  34. Lancet Neurol. 2005 Dec;4(12 ):827-40 - PubMed
  35. Annu Rev Genet. 1971;5:33-64 - PubMed
  36. Trends Parasitol. 2006 Nov;22(11):503-8 - PubMed
  37. PLoS One. 2009 Jun 09;4(6):e5848 - PubMed
  38. Blood. 2004 Nov 15;104(10):3364-71 - PubMed
  39. Parasitol Today. 1994 Oct;10(10):408-9 - PubMed
  40. Immunology. 2009 Jul;127(3):291-8 - PubMed
  41. J Biol Chem. 2007 Sep 28;282(39):28929-38 - PubMed
  42. Malar J. 2009 Apr 02;8:54 - PubMed
  43. PLoS One. 2007 Oct 10;2(10):e1020 - PubMed
  44. Nucleic Acids Res. 2007;35(20):6953-62 - PubMed
  45. BMC Genomics. 2008 Sep 18;9:425 - PubMed
  46. Neuropathol Appl Neurobiol. 2007 Oct;33(5):560-71 - PubMed
  47. Mol Aspects Med. 2004 Jun;25(3):221-360 - PubMed
  48. RNA Biol. 2013 Mar;10(3):367-70 - PubMed
  49. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4402-7 - PubMed
  50. Parasitol Res. 2012 Sep;111(3):1093-101 - PubMed
  51. Infect Immun. 2011 Jun;79(6):2379-84 - PubMed
  52. World J Gastroenterol. 2009 Dec 7;15(45):5633-40 - PubMed
  53. BMC Genomics. 2014 Jul 04;15:557 - PubMed
  54. J Infect Dis. 2003 Feb 1;187(3):461-6 - PubMed
  55. Bioinformatics. 2008 Jul 1;24(13):i50-8 - PubMed
  56. Parasitol Today. 1994 Oct;10(10):410-2 - PubMed
  57. Cell. 2007 Aug 10;130(3):413-26 - PubMed

Publication Types

Grant support