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Rounds MA, Crowder CD, Stratton CW, et al. Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry. Emerg Microbes Infect. 2012;1(12):e48doi: 10.1038/emi.2012.49.
Rounds, M. A., Crowder, C. D., Stratton, C. W., Ecker, D. J., Eshoo, M. W., & Tang, Y. W. (2012). Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry. Emerging microbes & infections, 1(12), e48. https://doi.org/10.1038/emi.2012.49
Rounds, Megan A, et al. "Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry." Emerging microbes & infections vol. 1,12 (2012): e48. doi: https://doi.org/10.1038/emi.2012.49
Rounds MA, Crowder CD, Stratton CW, Ecker DJ, Eshoo MW, Tang YW. Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry. Emerg Microbes Infect. 2012 Dec;1(12):e48. doi: 10.1038/emi.2012.49. Epub 2012 Dec 26. PMID: 26038414; PMCID: PMC3630909.
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Emerg Microbes Infect. 2012 Dec;1(12):e48. doi: 10.1038/emi.2012.49. Epub 2012 Dec 26.

Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry.

Emerging microbes & infections

Megan A Rounds, Christopher D Crowder, Charles W Stratton, David J Ecker, Mark W Eshoo, Yi-Wei Tang

Affiliations

  1. Ibis Biosciences , Inc., an Abbott company, Carlsbad, CA 92008, USA.
  2. Vanderbilt University Medical Center , Nashville, TN 37232, USA.
  3. Vanderbilt University Medical Center , Nashville, TN 37232, USA ; Memorial Sloan-Kettering Cancer Center , New York, NY 10065, USA.

PMID: 26038414 PMCID: PMC3630909 DOI: 10.1038/emi.2012.49

Abstract

Plasmodium vivax is a common cause of imported malaria in the USA, second only to P. falciparum. We present a case of P. vivax malaria in a child returning from India. P. vivax was initially diagnosed by standard methodology and detected retrospectively by use of broad-range PCR and electrospray ionization mass spectrometry using a panel of primers designed to detect vector-borne pathogens. This is the first reported case of P. vivax detection using PCR and electrospray ionization mass spectrometry.

Keywords: PCR and electrospray ionization mass spectrometry; Plasmodium vivax

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