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Gupta KL, Joshi K, Kohli HS, et al. Mucormycosis (zygomycosis) of renal allograft. Clin Kidney J. 2012;5(6):502-7doi: 10.1093/ckj/sfs130.
Gupta, K. L., Joshi, K., Kohli, H. S., Jha, V., & Sakhuja, V. (2012). Mucormycosis (zygomycosis) of renal allograft. Clinical kidney journal, 5(6), 502-7. https://doi.org/10.1093/ckj/sfs130
Gupta, Krishan L, et al. "Mucormycosis (zygomycosis) of renal allograft." Clinical kidney journal vol. 5,6 (2012): 502-7. doi: https://doi.org/10.1093/ckj/sfs130
Gupta KL, Joshi K, Kohli HS, Jha V, Sakhuja V. Mucormycosis (zygomycosis) of renal allograft. Clin Kidney J. 2012 Dec;5(6):502-7. doi: 10.1093/ckj/sfs130. Epub 2012 Nov 08. PMID: 26069793; PMCID: PMC4400555.
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Clin Kidney J. 2012 Dec;5(6):502-7. doi: 10.1093/ckj/sfs130. Epub 2012 Nov 08.

Mucormycosis (zygomycosis) of renal allograft.

Clinical kidney journal

Krishan L Gupta, Kusum Joshi, Harbir S Kohli, Vivekanand Jha, Vinay Sakhuja

Affiliations

  1. Department of Nephrology , Institute of Medical Education and Research , Chandigarh 160 012 , India.
  2. Department of Pathology , Postgraduate Institute of Medical Education and Research , Chandigarh 160 012 , India.

PMID: 26069793 PMCID: PMC4400555 DOI: 10.1093/ckj/sfs130

Abstract

Fungal infection is relatively common among renal transplant recipients from developing countries. Mucormycosis, also known as zygomycosis, is one of the most serious fungal infections in these patients. The most common of presentation is rhino-cerebral. Isolated involvement of a renal allograft is very rare. A thorough search of literature and our medical records yielded a total of 24 cases with mucormycosis of the transplanted kidney. There was an association with cytomegalovirus (CMV) infection and anti-rejection treatment in these patients and most of these transplants were performed in the developing countries from unrelated donors. The outcome was very poor with an early mortality in 13 (54.5%) patients. Renal allograft mucormycosis is a relatively rare and potentially fatal complication following renal transplantation. Early diagnosis, graft nephrectomy and appropriate antifungal therapy may result in an improved prognosis for these patients.

Keywords: cytomegalovirus infection; immunosuppression; mucormycosis; renal allograft

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