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Chapman AR, Gamble P, Pollock AM, et al. Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis. Clin Kidney J. 2013;6(6):626-9doi: 10.1093/ckj/sft104.
Chapman, A. R., Gamble, P., Pollock, A. M., & Joss, N. (2013). Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis. Clinical kidney journal, 6(6), 626-9. https://doi.org/10.1093/ckj/sft104
Chapman, Andrew R, et al. "Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis." Clinical kidney journal vol. 6,6 (2013): 626-9. doi: https://doi.org/10.1093/ckj/sft104
Chapman AR, Gamble P, Pollock AM, Joss N. Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis. Clin Kidney J. 2013 Dec;6(6):626-9. doi: 10.1093/ckj/sft104. Epub 2013 Aug 26. PMID: 26069832; PMCID: PMC4438358.
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Clin Kidney J. 2013 Dec;6(6):626-9. doi: 10.1093/ckj/sft104. Epub 2013 Aug 26.

Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis.

Clinical kidney journal

Andrew R Chapman, Paul Gamble, Anne Marie Pollock, Nicola Joss

Affiliations

  1. Aberdeen Royal Infirmary , Aberdeen , UK.
  2. Raigmore Hospital , Inverness , UK.

PMID: 26069832 PMCID: PMC4438358 DOI: 10.1093/ckj/sft104

Abstract

An 80-year-old woman presented with simultaneous increasing muscle weakness and nephrotic syndrome. A renal biopsy confirmed focal segmental glomerulosclerosis (FSGS). Her neurological diagnosis best fitted with a Guillain-Barre-like syndrome. There have been several cases of FSGS in combination with both conventional and atypical Guillain-Barre syndrome (GBS). Our patient was treated with high-dose steroids and resolution of both nephrotic syndrome and neurological symptoms occurred over 6 months. This article reviews all previously published presentations of this nature and discusses putative mechanisms for the development of concurrent FSGS and GBS.

Keywords: FSGS; Guillain–Barre syndrome; glucocorticoid therapy

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