ISRN Biochem. 2012 Dec 19;2012:506160. doi: 10.5402/2012/506160. eCollection 2012.
ISRN biochemistry
Thomas Kolter
PMID: 25969757 PMCID: PMC4393008 DOI: 10.5402/2012/506160
Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types. The paper provides a general overview on their structures, occurrence, and metabolism. Key functional, biochemical, and pathobiochemical aspects are summarized.