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Wu YP, Aspinwall LG, Michaelis TC, et al. Discussion of photoprotection, screening, and risk behaviors with children and grandchildren after melanoma genetic testing. J Community Genet. 2015;7(1):21-31doi: 10.1007/s12687-015-0243-3.
Wu, Y. P., Aspinwall, L. G., Michaelis, T. C., Stump, T., Kohlmann, W. G., & Leachman, S. A. (2016). Discussion of photoprotection, screening, and risk behaviors with children and grandchildren after melanoma genetic testing. Journal of community genetics, 7(1), 21-31. https://doi.org/10.1007/s12687-015-0243-3
Wu, Yelena P, et al. "Discussion of photoprotection, screening, and risk behaviors with children and grandchildren after melanoma genetic testing." Journal of community genetics vol. 7,1 (2016): 21-31. doi: https://doi.org/10.1007/s12687-015-0243-3
Wu YP, Aspinwall LG, Michaelis TC, Stump T, Kohlmann WG, Leachman SA. Discussion of photoprotection, screening, and risk behaviors with children and grandchildren after melanoma genetic testing. J Community Genet. 2016 Jan;7(1):21-31. doi: 10.1007/s12687-015-0243-3. Epub 2015 Jun 23. PMID: 26099287; PMCID: PMC4715817.
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J Community Genet. 2016 Jan;7(1):21-31. doi: 10.1007/s12687-015-0243-3. Epub 2015 Jun 23.

Discussion of photoprotection, screening, and risk behaviors with children and grandchildren after melanoma genetic testing.

Journal of community genetics

Yelena P Wu, Lisa G Aspinwall, Timothy C Michaelis, Tammy Stump, Wendy G Kohlmann, Sancy A Leachman

Affiliations

  1. Division of Public Health, Department of Family and Preventive Medicine, University of Utah, 375 Chipeta Way, Suite A, Salt Lake City, UT, 84108, USA. [email protected].
  2. Huntsman Cancer Institute, 2000 Circle of Hope Drive, Salt Lake City, UT, 84112, USA. [email protected].
  3. Department of Psychology, University of Utah, 380 South 1530 East, Salt Lake City, UT, 84112, USA.
  4. School of Medicine, University of Utah, 30 North 1900 East, Salt Lake City, UT, 84132, USA.
  5. Huntsman Cancer Institute, 2000 Circle of Hope Drive, Salt Lake City, UT, 84112, USA.
  6. Department of Dermatology, Oregon Health and Science University, 3303 Southwest Bond Avenue, Portland, OR, 97239, USA.

PMID: 26099287 PMCID: PMC4715817 DOI: 10.1007/s12687-015-0243-3

Abstract

The purpose of the current study was to examine changes in frequency of discussion about melanoma preventive behaviors among adults who received melanoma genetic test reporting and counseling and their children and grandchildren, correspondence of frequency of discussion with intentions, and content of discussions. Participants received CDKN2A/p16 testing and counseling (N = 24, 46 % p16-positive). Discussions about preventive behaviors were assessed before testing and 1 and 6 months post-testing. Intentions to discuss preventive behaviors and perceived preparedness to discuss risk were assessed post-testing. Open-ended questions assessed content of reported discussions. Discussion of preventive behaviors declined following test reporting, with more rapid decline reported by noncarriers. There was a large gap between the percentage of participants who intended to discuss preventive behaviors and who then reported discussions 1 and 6 months after counseling. Participants felt prepared to discuss melanoma risk but also suggested resources to facilitate discussions. Genetic test reporting and counseling alone did not sustain discussions about preventive behaviors for a hereditary cancer with children and grandchildren. The gap between intentions to have discussions and reported discussions has implications for augmentation of counseling to support at-risk families' discussions about preventive behaviors.

Keywords: CDKN2A/p16; Family communication; Genetic testing; Melanoma; Prevention

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