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NDT Plus. 2011 Jun;4(3):164-6. doi: 10.1093/ndtplus/sfr036. Epub 2011 Mar 29.

Case report: a rare cause of metabolic alkalosis.

NDT plus

Silvia M Titan, Otávio C E Gebara, Silvia H V Callas, Ana O Hoff, Paulo M Hoff, P C A Galvão

Affiliations

  1. Nephrology Division, Hospital das Clínicas, Sao Paulo University Medical School, Sao Paulo, Brazil.
  2. Hospital Sírio-Libanês, Sao Paulo, Brazil.
  3. Endocrinology Division, Fleury Laboratory, Sao Paulo, Brazil.

PMID: 25984146 PMCID: PMC4421598 DOI: 10.1093/ndtplus/sfr036

Abstract

A case of a 66-year-old white man with recent onset of oedema, hypertension, metabolic alkalosis and profound hypokalaemia is described. The initial laboratorial workup showed that urinary chloride concentration and potassium excretion were increased, suggesting a state of hyperaldosteronism. Nonetheless, renin activity was low and aldosterone levels were normal. The metabolic alkalosis seen in this case was due to a rare cause, the ectopic adrenocorticotropic hormone syndrome. A literature review in the subject is presented.

Keywords: ectopic adrenocorticotropic hormone syndrome; hypokalaemia; metabolic alkalosis

References

  1. Clin Endocrinol (Oxf). 1991 Jan;34(1):63-9 - PubMed
  2. Clin Endocrinol (Oxf). 2000 Mar;52(3):349-53 - PubMed
  3. Am J Kidney Dis. 1996 Oct;28(4):610-3 - PubMed
  4. Arch Intern Med. 1982 Jul;142(7):1387-9 - PubMed
  5. Ann N Y Acad Sci. 2002 Sep;970:134-44 - PubMed
  6. Arch Intern Med. 2004 Jul 26;164(14):1561-6 - PubMed
  7. Arch Intern Med. 1985 May;145(5):863-4 - PubMed
  8. J Clin Oncol. 1995 Jan;13(1):157-64 - PubMed
  9. Am J Med Sci. 2007 Dec;334(6):487-9 - PubMed
  10. J Am Soc Nephrol. 2005 May;16(5):1320-5 - PubMed

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