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El-Kader OA, Mohyelden K, Metwally AH, et al. Ethanolamine oleate vs. absolute ethanol as sclerosing agents for treating symptomatic simple renal cysts. Arab J Urol. 2014;12(4):294-8doi: 10.1016/j.aju.2014.09.003.
El-Kader, O. A., Mohyelden, K., Metwally, A. H., Sherif, M. H., Elnasher, A., Abdelhameed, H., & Azim, A. A. (2014). Ethanolamine oleate vs. absolute ethanol as sclerosing agents for treating symptomatic simple renal cysts. Arab journal of urology, 12(4), 294-8. https://doi.org/10.1016/j.aju.2014.09.003
El-Kader, Osman Abd, et al. "Ethanolamine oleate vs. absolute ethanol as sclerosing agents for treating symptomatic simple renal cysts." Arab journal of urology vol. 12,4 (2014): 294-8. doi: https://doi.org/10.1016/j.aju.2014.09.003
El-Kader OA, Mohyelden K, Metwally AH, Sherif MH, Elnasher A, Abdelhameed H, Azim AA. Ethanolamine oleate vs. absolute ethanol as sclerosing agents for treating symptomatic simple renal cysts. Arab J Urol. 2014 Dec;12(4):294-8. doi: 10.1016/j.aju.2014.09.003. Epub 2014 Oct 13. PMID: 26019965; PMCID: PMC4435759.
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Arab J Urol. 2014 Dec;12(4):294-8. doi: 10.1016/j.aju.2014.09.003. Epub 2014 Oct 13.

Ethanolamine oleate vs. absolute ethanol as sclerosing agents for treating symptomatic simple renal cysts.

Arab journal of urology

Osman Abd El-Kader, Khaled Mohyelden, Adel H Metwally, Mahmoud H Sherif, Ahmed Elnasher, Hussein Abdelhameed, Ahmed A Azim

Affiliations

  1. Department of Urology, Suez Canal University, Ismailia, Egypt.
  2. Department of Urology, Fayoum University, Fayoum, Egypt.
  3. Zagazig University Hospital, Zagazig, Egypt.

PMID: 26019965 PMCID: PMC4435759 DOI: 10.1016/j.aju.2014.09.003

Abstract

OBJECTIVES: To compare the efficacy and safety of ethanolamine oleate (EO) as a sclerosing agent, vs. absolute ethanol (AE), in the treatment of symptomatic simple renal cysts.

PATIENTS AND METHODS: Between November 2009 and October 2012, 46 patients were prospectively randomised into two groups. All patients presented with a simple renal cyst underwent ultrasonographic aspiration and injection of a sclerosing agent. In group 1, 25 patients had the cyst injected with EO, and in group 2, 21 were treated with AE. One injection was used in cysts of <200 mL and two injections were used in larger cysts. Complete and partial success were defined as complete cyst ablation or a >50% reduction in cyst volume with symptomatic relief, respectively. Patients were followed up using semi-annual ultrasonography and computed tomography for 2 years.

RESULTS: Sclerotherapy was technically successful in all patients. There was no significant difference in cyst volume between the groups. After ≈2 years of follow-up there was complete symptomatic relief in both groups, and the overall radiological success rate was 100% of both groups, at 79% complete and 21% partial in group 1, and 83% complete and 17% partial in group 2. The frequency of transient complications in the form of microscopic haematuria was 7% and 13%, and of low-grade fever in 4% and 10% in groups 1 and 2, respectively.

CONCLUSION: EO can replace AE as a sclerosing agent for symptomatic simple renal cysts, as it has comparable efficacy with higher safety and tolerance.

Keywords: AE, absolute ethanol; Absolute ethanol; Aspiration sclerotherapy; EO, ethanolamine oleate; Ethanolamine oleate; Simple renal cyst; US, ultrasonography

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