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Liver Cancer. 2015 Mar;4(1):51-69. doi: 10.1159/000367728.

Hong Kong consensus recommendations on the management of hepatocellular carcinoma.

Liver cancer

Ronnie Tung-Ping Poon, Tom Tan-To Cheung, Philip Chong-Hei Kwok, Ann-Shing Lee, Tat-Wing Li, Kwok-Loon Loke, Stephen Lam Chan, Moon-Tong Cheung, Tak-Wing Lai, Chin-Cheung Cheung, Foon-Yiu Cheung, Ching-Kong Loo, Yiu-Kuen But, Shing-Jih Hsu, Simon Chun-Ho Yu, Thomas Yau

Affiliations

  1. Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong, SAR (China).
  2. Department of Radiology and Imaging, Queen Elizabeth Hospital, Hong Kong, SAR (China).
  3. Department of Clinical Oncology, Tuen Mun Hospital, Hong Kong, SAR (China).
  4. Department of Medicine, Pamela Youde Nethersole Eastern Hospital, Hong Kong, SAR (China).
  5. Department of Radiology and Organ Imaging, United Christian Hospital, Hong Kong, SAR (China).
  6. Department of Clinical Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, SAR (China).
  7. Department of Surgery, Queen Elizabeth Hospital, Hong Kong, SAR (China).
  8. Department of Surgery, Princess Margaret Hospital, Hong Kong, SAR (China).
  9. Department of Surgery, Tuen Mun Hospital, Hong Kong, SAR (China).
  10. Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, SAR (China).
  11. Department of Medicine and Geriatrics, Kwong Wah Hospital, Hong Kong, SAR (China).
  12. Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, SAR (China).
  13. Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, SAR (China).

PMID: 26020029 PMCID: PMC4439785 DOI: 10.1159/000367728

Abstract

BACKGROUND: Hepatocellular carcinoma (HCC) is particularly prevalent in Hong Kong because of the high prevalence of chronic hepatitis B (CHB) infection; HCC is the fourth commonest cancer in men and the seventh commonest in women, and it is the third leading cause of cancer death in Hong Kong. The full spectrum of treatment modalities for HCC is available locally; however, there is currently no local consensus document detailing how these modalities should be used.

SUMMARY: In a series of meetings held between May and October 2013, a multidisciplinary group of Hong Kong clinicians - liver surgeons, medical oncologists, clinical oncologists, hepatologists, and interventional radiologists - convened to formulate local recommendations on HCC management. These recommendations consolidate the most current evidence pertaining to HCC treatment modalities, together with the latest thinking of practicing clinicians engaged in HCC management, and give detailed guidance on how to deploy these modalities effectively for patients in various disease stages.

KEY MESSAGES: Distinct from other regional guidelines, these recommendations provide guidance on the use of antiviral therapy to reduce the incidence of HCC in CHB patients with cirrhosis and to reduce recurrence of CHB-related HCC.

Keywords: Consensus; Hepatocellular carcinoma; Hong Kong

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