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Springerplus. 2015 Jun 19;4:280. doi: 10.1186/s40064-015-1074-8. eCollection 2015.

Dietary supplemental vitamin B6 increases carnosine and anserine concentrations in the heart of rats.

SpringerPlus

Sofya Suidasari, Tomoko Hasegawa, Noriyuki Yanaka, Norihisa Kato

Affiliations

  1. Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima, 739-8528 Japan.

PMID: 26101732 PMCID: PMC4472654 DOI: 10.1186/s40064-015-1074-8

Abstract

This study was performed to examine the effect of dietary level of vitamin B6 on the concentrations of carnosine and anserine, antioxidants, in the heart of rats. Analysis using UPLC-MS/MS showed that the concentrations of these dipeptides in the 7 and 35 mg pyridoxine HCl/kg groups were significantly higher than those in the 1 mg pyridoxine HCl/kg group, implying the novel role of dietary vitamin B6 as a determinant of the dipeptides favorable for heart.

Keywords: Anserine; Carnosine; Heart; UPLC–MS/MS; Vitamin B6

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